Wuxi Zhiyan Biotechnology Co., Ltd

Liyong Du

Yue Wang

Jingguo Yang

Beilei Cai

Zhihui Tian

Shuyan Yang

Zixuan Xu

Disclosed are a liquid supramolecular self-recognition system of low-pH azelaic acid, and a preparation method therefor and application thereof. The preparation method for the ternary liquid supramolecular self-recognition system of low-pH azelaic acid/succinic acid/panthenol includes the following steps: mixing and heating azelaic acid, succinic acid, and panthenol in a molar ratio of 1:0.5:1-1:10:10 in a sealed container to obtain a mixture and heated at 60-120° C. for more than 1-24 hours, and cooling down the mixture to room temperature after the heating is completed to obtain the liquid supramolecular self-recognition system of low-pH azelaic acid. The preparation method is green and simple, and the resulting supramolecular self-recognition system can effectively improve the solubility of azelaic acid, and have excellent stability without precipitation. In addition, the supramolecular self-recognition system for the azelaic acid/succinic acid/panthenol prepared in the present disclosure is in a liquid form, and can be directly applied to subsequent formulations without special treatment.

Growing community of inventors

Wuxi, China

Liyong Du