City of Hope

Lixin Yang

David A Horne

Samuel Rahbar

Sanjay Awasthi

Christopher Lincoln

James Lester Figarola

Rachael Mooney

George Somlo

Monika Polewski

Sharad S Singhal

Jyotasana Singhal

One aspect of the disclosure relates to the use of derivatives of dichlorophenyl urea for treating cancers.

Compound for treating cancer and diabetes

One aspect of the disclosure relates to derivatives of aryl and heterocyclic ureido aryl and heterocyclic carboxamido isobutyric acids, dichlorophenyl urea, curcumin, and 1,3-diazetidine-2,4-dione, and pharmaceutical compositions thereof. The derivatives disclosed herein can modulate development of adipocytes and various cancer cells, including resistant cancer cells and cancer stem cells. Another aspect of the disclosure relates to the use of the derivatives and pharmaceutical compositions disclosed herein in treatment of obesity and various cancers.

Modulators of development of adipocyte and cancer cells

Growing community of inventors

Arcadia, CA, United States of America

Lixin Yang