Zhuhai United Laboratories Co., Ltd.

Liwei Mu

Liang Fang

Shuhui Chen

Wenyuan Qian

Changqing Wei

Weiwei Mao

Shuai Wang

Miao Fang

Shouting Wu

Tingting Yu

Degang Wang

The present invention discloses the crystal forms as a JAK inhibitor and their application in the preparation of drugs for the treatment of JAK1 or/and TYK2 related diseases.

Crystalline form of JAK inhibitor and application thereof

Disclosed is the use of a JAK inhibitor [1,2,4]-triazolo-[1,5-a]0pyridine compound in the preparation of drugs for treating autoimmune, inflammatory or allergic diseases, or diseases such as transplant rejection. The JAK inhibitor [1,2,4]-triazolo-[1,5-a]-pyridine compound comprises a compound as shown in formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof. The JAK inhibitor has a good efficacy in animal model tests of diseases such as autoimmune, inflammatory or allergic diseases.

Use of JAK inhibitors in preparation of drugs for treating JAK kinase-related diseases

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Guangdong, China

Liwei Mu