Cargill Inc.

Evonik Roehm Gmbh

Evonik Degussa Gmbh

Evonik Rohm Gmbh

Liv Reinecke

Steffen Schaffer

Thomas Haas

Achim Marx

Hans H Liao

Eileen Spindler

Wendy Kathleen Ribble

Tanya Lipscomb

Katrin Grammann

Jan Wolter

Catherine B Poor

Ronald J Evans

Anja Thiessenhusen

Markus Poetter

Dirk Weuster-Botz

Markus Pötter

Brittany Robinson

Tim Koehler

Brittany Prather

Yvonne Schiemann

Dave A Hogsett

Jasmin Corthals

David A Hogsett

Harald Krispin

Markus Buchhaupt

Wilhelm Krispin

Nicole Potgrave

Brittany L Prather

Tanya Warnecke Lipscomb

Eileen C Spindler

Maik Olfert

Monika Johanna Krispin

A microbial cell is used for producing at least one fatty acid ester, wherein the cell is genetically modified to contain (i) at least one first genetic mutation that enables the cell to produce at least one fatty acid and/or acyl coenzyme A (CoA) thereof by increased enzymatic activity in the cell relative to the wild type cell of malonyl-CoA dependent and malonyl-ACP independent fatty acyl-CoA metabolic pathway, wherein the fatty acid contains at least 5 carbon atoms; and (ii) a second genetic mutation that increases the activity of at least one wax ester synthase in the cell relative to the wild type cell and the wax ester synthase has sequence identity of at least 50% to a polypeptide of SEQ ID NO: 1-8 and combinations thereof or to a functional fragment of any of the polypeptides for catalyzing the conversion of fatty acid and/or acyl coenzyme A thereof to the fatty acid ester.

Production of fatty acids esters

The invention relates to a cell which has been genetically modified so as to be capable of producing more 2-hydroxyisobutyric acid or more polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units than its wild type, characterized in that 2-hydroxyisobutyric acid or polyhydroxyalkanoates containing 2-hydroxyisobutyric acid monomer units are produced via acetoacetyl-coenzyme A as intermediate and 3-hydroxybutyryl-coenzyme A as precursor.

Recombinant cell producing 2-hydroxyisobutyric acid

The present invention relates to a method for producing C4 bodies, preferably butyric acid and/or butanol, comprising the steps contacting an aqueous medium comprising an acetogenic bacterial cell in an aqueous medium with syngas and incubating the mixture obtained in step a) at a temperature between 0 and 100&#xb0; C. for at least 30 minutes, wherein the aqueous medium comprises, in step b), ethanol and/or acetate at a total combined concentration is at least 0.1 gL.

Biotechnological method for producing butanol and butyric acid

The invention relates to the use of a protein homologous to a MeaB protein for increasing the enzymatic activity of a 3-hydroxycarboxylic acid-CoA mutase, a fusion protein comprising a 3-hydroxycarboxylic acid-CoA mutase and a protein sequence homologous to a MeaB protein and an enzymatic method for producing 2-hydroxyisobutryric acid.

Use of a protein homologous to a MeaB protein for increasing the enzymatic activity of a 3-hydroxycarboxylic acid-CoA mutase

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Essen, Germany

Liv Reinecke