Janssen Pharmaceutica Nv

Liu Y Tang

Hariharan Venkatesan

Cheryl A Grice

Ronald L Wolin

Laurent Gomez

John J M Wiener

Michael D Hack

Brett D Allison

Kimberly Schwarz

Alejandro Santillán, Jr

Timothy W Lovenberg

Charles Q Huang

Karen Joy Shaw

Brian J Morrow

S Timothy Motley

Tristin K Barclay

Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.

Bicyclic pyrazole compounds as antibacterial agents

The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.

Aryl piperidine amides

Certain &#x3b1;-, &#x3b2;-, and &#x3b3;-amino acid derivatives are disclosed as selective GlyT2 inhibitors for the treatment of central nervous system (CNS) conditions such as muscle spasticity, tinnitus, epilepsy and neuropathic pain.

GlyT2 modulators

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San Diego, CA, United States of America

Liu Y Tang