Millennium Pharmaceuticals Limited

Liting Ma

Alexandra E Gould

Dylan Bradley England

He Xu

Kenneth M Gigstad

Sean J Harrison

Emily Frances Calderwood

Shih-Chung Huang

Sharmila Adhikari

Disclosed are chemical entities which are compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein R, R, and Rhave the values described herein. Chemical entities according to the disclosure can be useful as inhibitors of ATG7. Further provided are pharmaceutical compositions comprising a chemical entity of the disclosure and methods of using the compositions in the treatment of cancer. 

ATG7 inhibitors and the uses thereof

This invention provides compounds of formula (I): 

Substituted hydroxamic acids and uses thereof

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Needham, MA, United States of America

Liting Ma