Rutgers, The State University of New Jersey

Woods Hole Oceanographic' Institution

Liti Haramaty

Paul G Falkowski

Eileen White

Benjamin A S Van Mooy

Richard Lutz

Kay Daniel Bidle

Assaf Vardi

Helen F Fredricks

Eric Andrianasolo

Eric H Andrianasolo

The invention provides a compound of formula (I): (I) wherein R-Rhave any of the values defined in the specification, as well as compositions comprising a compound of formula (I) and methods for treating diseases (e.g. cancer). 

Ceramide derivatives as anticancer agents

Phytoplankton represent a potential source of bioactive compounds. The present disclosure provides, inter alia, methods for identifying glycerolipids and apoptosis-inducing sphingosine-like lipids from virally-infected phytoplankton.

Bioactive compounds from phytoplankton containing glycosidic residue for apoptosis and cancer treatment

Methods for obtaining bioactive compounds from phytoplankton

Compounds of formulas I-IV: (I), (II), (III) (IV), wherein: Rand R-Rare independently selected from H and 1-3 carbon lower alkyl; and Rand Rare independently selected from H, 1-3 carbon lower O II alkyl, and &#x2014;C&#x2014;R, wherein Ris 1-3 carbon lower alkyl. Pharmaceutical compositions, which include any of Compounds I-IV and a pharmaceutically acceptable carrier, methods of inducing tumor cell apoptosis by administering to a patient in need thereof an effective amount of any of Compounds I-IV, and methods for obtaining any of Compounds I-IV by extracting the compound from coral are also provided. 

Compositions and methods for treating cancer

Growing community of inventors

East Brunswick, NJ, United States of America

Liti Haramaty