Delmar Chemicals Inc.

Lise A Hughes

Rudolf Kubela

Vaclav Musil

Ctirad Podesva

The present invention is concerned with novel 2-unsubstituted-3-phenylindolines acid addition salts thereof. These compounds have been found to have valuable pharmacological properties indicative of possible utility, inter alia, of controlling coagulation of the blood and as hypoglycemic agents. The invention also provides novel processes for producing the novel compounds and pharmaceutical compositions containing same as active ingredients.

Phenylindolines

The present invention is concerned with novel 2-unsubstituted-3-phenylindolines and acid addition salts thereof. These compounds have been found to have a valuable pharmacological property indicative of possible utility in controlling coagulation of the blood.

3-Phenylindolines

The present invention is concerned with novel 2-unsubstituted-3-phenylindolines and acid addition salts thereof. These compounds have been found to have valuable pharmacological properties indicative of possible utility, inter alia, of controlling coagulation of the blood and as hypoglycemic agents. The invention also provides novel processes for producing the novel compounds and pharmaceutical compositions containing same as active ingredients.

Phenylindolines and process for their production

The present invention is concerned with novel 7-oxabicyclo-[2.2.1]-5-heptene derivatives and a process for their production. These compounds are useful intermediates in the production of various pharmacologically active compounds.

2,3-Disubstituted 7-oxabicyclo-[2.2.1]-5-heptene

The present invention is concerned with novel cyclopentene and cyclopentane derivatives which have pharmacological, particularly analgesic and antiinflammatory activity, and are also useful intermediates in the preparation of other pharmacologically active compounds.

Novel cyclopentene and cyclopentane derivatives

Certain 2-substituted-4-substituted-1(2H)-phthalazinone compounds have hypotensive activity. Such compounds are used in pharmaceutical compositions. Processes of preparing them and the intermediate compounds are disclosed.

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Ville de Lery, Canada

Lise A Hughes