Incept, LLC

Imperative Care, Inc.

Lisa M Young

Yi Yang

Brandon Yee

Ashoor Shahbazi Yourgenlow

Farhad Khosravi

Fred Khosravi

Ryan Taylor Krone

Marc Russell

A neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a side wall defining a central lumen. The side wall includes a tubular inner liner, a tie layer separated from the central lumen by the inner liner, a helical coil at least partially overlapping the tie layer, and a tubular braid. A first section of adjacent windings of the helical coil can be spaced farther apart from each other than a second section of adjacent windings of the helical coil.

Neurovascular catheter

A neurovascular catheter having an elongate flexible tubular body. The body can have a catheter distal face residing on a first plane being at a first nonorthogonal angle relative to the longitudinal axis. The body can have a radiopaque marker being positioned in a distal zone of the tubular body and being proximal to the catheter distal face. The marker can have a marker distal face at least partially residing on a second plane being at a second nonorthogonal angle relative to the longitudinal axis. The first plane can be approximately parallel to the second plane.

Catheter having angled tip

A neurovascular catheter having an atraumatic navigational tip is disclosed. The catheter includes an elongate flexible tubular body, a distal zone of the tubular body comprising: a tubular inner liner; a helical coil surrounding the inner liner and having a distal end, a tubular jacket surrounding the helical coil, and extending distally beyond the helical coil distal end to terminate in a catheter distal face, and a tubular radiopaque marker embedded in the tubular jacket. The catheter distal face comprises a first section that resides on a first plane which crosses a longitudinal axis of the tubular body at a first angle within the range of from about 35 degrees to about 55 degrees, and a second section that resides on a second plane which crosses the longitudinal axis of the tubular body at a second angle within the range from about 55 degrees to about 90 degrees.

Devices and methods for removing obstructive material, from an intravascular site

A neurovascular catheter having an angled distal tip has an elongate flexible tubular body with a proximal end, a distal end and a side wall defining a central lumen. The side wall has a helical coil. A tubular jacket surrounds the helical coil, and extending distally beyond the helical coil distal end to terminate in a catheter distal face. A tubular radiopaque marker is embedded in the tubular jacket in between the distal end of the coil and the distal face. The distal face resides on a plane which crosses a longitudinal axis of the tubular body at an angle within the range of from about 35 degrees to about 55 degrees. The marker has a proximal face that is approximately perpendicular to the longitudinal axis and a distal face that resides on a plane which crosses the longitudinal axis at an angle within the range of from about 35 degrees to about 55 degrees.

Enhanced flexibility neurovascular catheter with tensile support

A method of making a high flexibility distal zone on a neurovascular catheter is provided. The method includes the steps of dip coating a removable mandrel to form a tubular inner layer on the mandrel, coating the tubular inner layer with a tie layer, applying a helical coil to the outside of the tie layer, positioning a plurality of tubular segments, heating the tubular segments to form the high flexibility distal zone on the neurovascular catheter; and removing the mandrel.

Method of making an enhanced flexibility neurovascular catheter

Neurovascular catheter having atraumatic angled tip

A neurovascular aspiration catheter has an elliptical distal aspiration port. The catheter has an elongate flexible tubular body comprising a distal port and a side wall defining a central lumen in communication with the port. A tubular radiopaque marker is embedded in the side wall and has a proximal face and a distal face. The distal face of the radiopaque marker inclines at an angle within a range of from about 45 degrees to about 80 degrees relative to the longitudinal axis of the central lumen. The distal port comprises an elliptical opening with an area that is at least about 105% of a cross-sectional area of the central lumen.

Neurovascular aspiration catheter with elliptical aspiration port

A neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the tubular body includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, an outer jacket surrounding the helical coil, and an opening at the distal end. Adjacent windings of the helical coil are spaced progressively further apart in the distal direction. The opening at the distal end of the tubular body is enlargeable from a first inside diameter for transluminal navigation to a second, larger inside diameter to facilitate aspiration of thrombus into the lumen.

Neurovascular catheter with enlargeable distal end

A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.

Enhanced flexibility neurovascular catheter

A method of making a high flexibility distal zone on a neurovascular catheter is provided. The method includes the steps of dip coating a removable mandrel to form a tubular inner layer on the mandrel, coating the tubular inner layer with a soft tie layer, applying a helical coil to the outside of the tie layer, positioning a plurality of tubular segments on the helical coil, heating the tubular segments to form the high flexibility distal zone on the neurovascular catheter; and removing the mandrel. The plurality of segments have durometers that decrease in a distal direction. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.

A neurovascular catheter extension segment is provided, such as for distal neurovascular access or aspiration. The neurovascular catheter extension segment includes 1) an elongate flexible control wire having a proximal end and a distal end and 2) a tubular extension segment having a side wall defining a central lumen carried by the distal end of the control wire. The side wall of the tubular extension segment includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, and an outer jacket surrounding the helical coil. The extension segment may be introduced into the proximal end of a neurovascular catheter and advanced distally to extend beyond the catheter and thereby extend the reach of the catheter.

Neurovascular catheter extension segment

An enhanced flexibility neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes an outer jacket surrounding a helical coil, and the outer jacket is formed from a plurality of tubular segments positioned coaxially about the coil. A proximal one of the tubular segments has a durometer of at least about 60D, and a distal one of the tubular segments has a durometer of no more than about 35D. An axially extending filament within the side wall extends at least about the most distal 10 cm of the length of the catheter. The axially extending filament serves as a tension support and resists elongation of the catheter wall under tension, such as when the catheter is being proximally retracted through tortuous vasculature.

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Mountain View, CA, United States of America

Lisa M Young