Lankenau Institute for Medical Research

Dynamis Therapeutics, Inc.

Aviana Molecular Technologies, LLC

Lisa Laury-Kleintop

George C Prendergast

Annette Tobia

Herman Rutner

James Duhadaway

Laura Mandik-Nayak

Arturo Bravo Nuevo

Biosensor components (chips) are described based on direct biocoating processes that result in the tenacious and stable, noncovalent (believed to be chemisorptive) binding of anchor substances such as avidin(s) other proteins having specific binding partners or oligo- or poly-nucleotides onto any piezo-electrically active crystal surface. The resulting platform technology can be developed for a variety of biosensors with specific applications in biological assays. The table mono layers of the anchor substances forms reactive layers, ready to bind a capture reagent such as a biot-inylated antibody for capture and detection of analytes in biologic fluid samples. Although the processes described herein can be performed on any type of piezoelectric material in any number of configurations, some embodiments are directed to a biosensor with the foregoing biocoating onto a particular acoustic plate mode biosensor and where the interdigitated transducers (IDTs) are present on the opposite side of the crystal's biocoated film.

Biocoated piezoelectric biosensor platform for point-of-care diagnostic use

Anti-RhoB antibodies, compositions comprising the same, and methods for the treatment of autoimmune and inflammatory diseases using the anti-RhoB antibodies are disclosed.

Anti-RhoB antibodies

The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.

Methods for maintaining or improving health, well-being and/or a physiological function in a subject

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Ambler, PA, United States of America

Lisa Laury-Kleintop