Biogen Idec Ma Inc.

Nestec S.a.

Applied Proteomics, Inc.

Lisa Croner

Alexey Alexandrovich Lugovskoy

Scott Glaser

Brian Miller

Stephen John Demarest

Xiufeng Wu

William Brian Snyder

Norman Wang

Sharat Singh

John E Blume

Fred Princen

Steven Lockton

Thomas Stockfisch

Jeffrey Jones

Frederick A Fletcher

Ryan Benz

Athit Kao

Roslyn Dillon

Jia You

Bruce Wilcox

Disclosed herein are panels related to the diagnosis or recognition of colon and colorectal cancer in a subject. The disclosed panels and related methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a report for clinical management.

Protein biomarker panels for detecting colorectal cancer and advanced adenoma

The invention is based, at least in part, on the development of stabilized binding molecules that consist of or comprise a stabilized scFv and methods for making such stabilized molecules.

Stabilized polypeptide compositions

The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and UC, and to differentiate between CD and UC with increased accuracy.

Methods for improving inflammatory bowel disease diagnosis

Growing community of inventors

San Diego, CA, United States of America

Lisa Croner