Tsinghua University

Capitalbio Corporation

Liqing Duan

Dong Wang

Guoqing Wang

Wanli Xing

Huafang Gao

Kaijun Zhao

Jiaming Ye

Pinhong Wang

Jinxiu Zhang

Xiumei Song

A hybridization system is provided, which comprises a biological chip having a substrate () with a probe dot matrix () and a cover plate () with at least two through-holes (), where a hybrid chamber () is formed between the substrate () and the cover plate (), at least two fluid channels () are interconnected respectively with the hybrid chamber () by the two through-holes (), and a fluid control device is interconnected with the fluid channels (). The biological chip hybridization system integrates hybridizing, cleaning and drying functions, uses power provided by the fluid control device as the drive force for promoting the liquid flow for automatically reciprocation flow in the fluid channels () and the chamber () to achieve a dynamic hybridization, thus improving the hybrid efficiency and uniformity, and achieving automatic control.

Biological chip hybridization system

Growing community of inventors

Beijing, China

Liqing Duan