University of Minnesota

Liqiang Chen

Teng Ai

Swati Sudhakar More

The invention provides compounds having the general formula I: and salts thereof, wherein the variables R, R, R, L, L, L, A, B, C, X, Y, Z, E, m, n, and p have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Anticancer compounds

The invention provides compounds of formula (I): wherein, A, C, D, X, and Y have any of the values defined in the specification, and salts thereof. The compounds are SIRT2 inhibitors and are useful for treating SIRT2 associated conditions.

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Minneapolis, MN, United States of America

Liqiang Chen