Jiangnan University

Jiangsu Xcmg Construction Machinery Research Institute Ltd.

Liping Zhang

Caihua Ni

Ren Liu

Shaohai Fu

Gang Shi

Min Li

Xinxin Sang

Anli Tian

Gang Wang

Chengcheng Wang

Can Wang

Haijun Wang

He Liu

Dawei Wang

Chunxia Wang

Zhiquan Li

Dong Wang

Yangyang Xu

Wenlong Wang

Xinyi Dong

Chen Liu

Yuanyuan Ding

Ang Ji

Yamin Zhou

Lei Tao

Ying Zhao

Liangan Wang

Ying Tan

Yi Zhu

Mingfei Sheng

Xiaofeng Xia

Guangzhi Xu

Zhenle Tian

Jingjing Li

Xiaojun Jiang

Hongyun Peng

Mingming Liu

A meshing structure for plate welding, and a tack-free welding device and method are provided. The device comprises a connecting frame, a welding gun, and a cutting mechanism, the welding gun is fixed on the connecting frame, and the cutting mechanism is connected to the connecting frame. The meshing structures are disposed on welded plates, and after being assembled, the two plates can be restrained by the meshing structures in multiple dimensions. Before welding, edges of the plates are cut according to the form of the meshing structures, then the plates are assembled and meshed; after the position of the welding gun is adjusted, the cutting mechanism and the welding gun are driven by a welding robot or a special welding machine to move along a weld; and the meshing structures are removed by the cutting mechanism, and then normal welding is performed by the welding gun.

Meshing structure for plate welding and tack-free welding device and method

The disclosure discloses a phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid flame retardant and application thereof, and belongs to the technical field of halogen-free flame retardant. Components of the phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid material in the disclosure include, by weight, 1-2 parts of molybdenum disulfide, 1-1.5 parts of zinc salt, 5-8 parts of a nitrogen-containing compound and 5-10 parts of a phosphorus-containing compound. As a flame retardant, the hybrid material of the disclosure effectively exerts an organic-inorganic synergistic flame retardant effect; the flame retardant efficiency of molybdenum disulfide is improved; the addition amount of the flame retardant in a matrix is reduced; the mechanical properties of the matrix can be improved at the same time; and the material has a very good application prospect.

Phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid flame retardant and application thereof

The disclosure belongs to the technical field of material science, and particularly relates to a method for preparing a high sensitivity temperature sensitive reversible color-changing microcapsule. According to the method, a series of novel fluorane dyes are designed and synthesized, the color-changing performance can be achieved without a color developing agent, the fluorane dyes are compounded with a phase change material according to a certain proportion, a series of two-component reversible temperature sensitive color-changing dyes are prepared, and then a two-component reversible thermochromic microcapsule with good color performance and color-changing response performance is prepared by adopting a solvent evaporation method. The two-component reversible thermochromic microcapsule provided by the disclosure can effectively alleviate the color lag phenomenon of a traditional three-component thermochromic capsule.

Method for preparing high sensitivity temperature sensitive reversible color-changing microcapsule

The invention discloses a coordination type zirconium phosphotungstate catalyst and its application in catalytic hydrogenation of furfural, belonging to the field of heterogeneous catalysis. The zirconium phosphotungstate catalyst prepared by the invention not only has good catalytic effect on the conversion of furfural to furfuryl alcohol, but also has mild reaction conditions. The yield of solid line furfuryl alcohol can be 98% if it can be reacted for 1 h at 120 ° C., and the amount of catalyst is less, which greatly reduces the energy consumption in the prior art. In addition, the zirconium phosphotungstate prepared by the invention is easy to separate, has good stability for catalyzing the hydrogenation of furfural to furfuryl alcohol, and is a new, efficient and green catalyst.

Coordination zirconium phosphotungstate catalyst and its application in catalytic hydrogenation of furfural

The invention provides a making method of modified polyvinyl alcohol embolic microspheres. First, polyvinyl alcohol dimethyl sulfoxide solution is added to acryloyl chloride dichloromethane solution for reaction, then taurine solution is added to the above solution for further reaction, so that functional groups are introduced into the side chains of polyvinyl alcohol, then blank microspheres are prepared by suspension crosslinking method, and finally, drug-loaded modified polyvinyl alcohol embolic microspheres are prepared. The invention aims at improving the drug loading rate and drug loading speed of the microspheres. Through modification, the crystallinity of polyvinyl alcohol is weakened, the swelling in water is accelerated, and the application effect of the microspheres is improved.

Method for making modified polyvinyl alcohol embolic microsphere

The disclosure discloses a method of preparing electric and temperature dual-control bi-stable color-changing dyes and microcapsules, belonging to the technical fields of fine chemicals and materials science. According to the disclosure, after an electrolyte, a leuco dye and an organic solid material are mixed according to 1:(2-10):(15-50), a series of electric and temperature dual-control bi-stable color-changing dye compounds having a color change temperature range of &#x2212;5&#xb0; C. to +80&#xb0; C. can be prepared. The dye compounds change color under cooperative control of electricity and temperature, and can be continuously stable at a certain color change state according to different conditions, and finally achieve controllable color change conditions and controllable color change stable states. When being driven by voltage and temperature, the dual-control bi-stable color-changing microcapsules prepared according to the disclosure achieve controllable color change performance and color change stable states, and have the driving voltage being lower than 10 V (much lower than the human body safety voltage 36 V).

Method of preparing electric and temperature dual-control bi-stable color-changing dyes and microcapsules

A method for making xanthan gum copolymer nanomicelles comprising: 1) degrading xanthan gum in aqueous solution to obtain degraded xanthan gum; 2) preparing xanthan gum bromide from the degraded xanthan gum; 3) preparing xanthan gum copolymer from the xanthan gum bromide and 4) making the gum copolymer nanomicelles from the xanthan gum copolymer. The xanthan gum copolymer nanomicelles have good morphological regularity, good biocompatibility and stable performance as an anticancer drug carriers.

Method for preparation of xanthan gum copolymer nanomicelles

A method for making reduction sensitive nano micelles comprising: 1) dissolving taurine in distilled water, and adding sodium hydroxide solution; 2) dissolving acryloyl chloride in dichloromethane, reacting at 25&#xb0; C.; dissolving lipoic acid in toluene and adding hydroxyethyl methacrylate, reacting at 85&#xb0; C.; 3) dissolving N-acryloyltaurine and lipoic acid methacryloyloxyethyl ester and reacting at 60&#x2dc;65&#xb0; C., dropping the polymer solution into deionized water, adding dithiothreitol and reacting at 25&#x2dc;30&#xb0; C. to obtain reduction sensitive nano micelles after freeze-drying. The nano micelles have regular morphology and uniform distribution, and can be used as drug carriers for controlled release.

Method for making reduction sensitive nano micelles

A method of preparing degradable and environment responsive composite microgels, belonging to polymer material synthesis and biomaterial technology fields. Firstly, a copolymer of L-malic acid and 6-hydroxyhexanoate is prepared; then, N,N,N',N&#x2032;-tetramethyl cystamine is prepared. The copolymer and N,N,N&#x2032;,N&#x2032;-tetramethyl cystamine are mixed in an organic solvent to form a mixed solution which is added into excess distilled water to produce composite microgels. The microgels have advantages of mild preparing conditions, fast reaction speed without catalysts, no impurity remained, and controllable degradation rate. The microgels can load anticancer drug doxorubicin hydrochloride, showing environment responsive controlled release due to introduction of carboxyl groups and disulfide bonds.

Method of preparing degradable and environment responsive composite microgels

Disclosed is a method for preparing self-dispersing nano carbon black based on a thiol-ene click reaction. A sol-gel technique is used to graft a coupling agent containing a carbon-carbon double bond onto the surface of the carbon black, and a functional molecular chain is grafted onto the surface of the carbon black by a thiol-ene click reaction with a mercapto compound. The self-dispersing nano carbon black is obtained after centrifugation, washing and drying. The method is simple and easy to operate, has a high grafting rate, and can prepare self-dispersing nano carbon black adaptable to different systems by selecting mercapto compounds with different functional groups.

Method for preparing self-dispersing nano carbon black based on a thiol-ene click reaction

The invention discloses a preparation method of pH/reduction responsive polyamino acid zwitterionic nanoparticles, which belongs to the technical field of polymer synthesis and biomedical materials. In the invention aliphatic amines are used to initiate ring-opening polymerization of &#x3b3;-benzyl-L-glutamate-N-carboxylic anhydride, and the obtained poly(&#x3b3;-benzyl-L-glutamate) reacts with L-lysine to form azwitterionic polymer. The zwitterionic polymer is crosslinked by cysteamine, producing pH/reduction responsive polyamino acid zwitterionic nanoparticles after purification. The nanoparticles are pH responsive and resistant to non-specific protein adsorption. Because cysteamine contains disulfide bonds, the nanoparticles have sensitive reductive responsiveness and can load anticancer drugs for controlled release at the target site of cancer.

Method of preparing pH/reduction responsive polyamino acid zwitterionic nanoparticles

The present invention discloses modified epoxy acrylates and the solder resist containing the epoxy modified acrylates, belonging to the synthetic resin field. In this invention, modified epoxy acrylates are prepared by introducing long fatty hydrocarbon chain as the branched chain into the carboxylated epoxy acrylates. The as-prepared solder resist containing this modified epoxy acrylates maintains the excellent property of photosensitive solder resist such as good adhesion, hardness, solvent resistance and weather resistance which facilities sensitivity and alkaline development during exposure simultaneously. This has led to good water resistance, electrical insulation of the cured products. Furthermore, the cured product also shows good flexibility which improves its application in photosensitive imaging ink materials.

Preparation of modified epoxy acrylates and solder resist containing modified epoxy acrylates

Hybrid amphiphilic star copolymer nano micelles are prepared in the invention. Cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes is selected as the inorganic part, and L-glutamic benzyl ester&#x2014;five membered ring anhydride is ring-opening polymerized by the initiation of amino groups on the surface of cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes, producing copolymers with cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes as nucleus and poly (L-glutamic-benzyl ester) as arms. The copolymers reacts with monomethoxy poly (ethylene glycol) carboxylic acid by condensation. Finally, the benzyl groups in the side chains of poly (L-glutamic acid-benzyl ester) are converted into hydrazine groups by acylhydrazination to obtain hybrid amphiphilic star copolymer nano micelles. The micelles can load doxorubicin, they are safe to human body and have good application prospects.

Method for preparation of hybrid amphiphilic star copolymer nano micelles

Disclosed is a preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles, falling within the technical field of biomedical materials. The method comprises: synthesizing thiocinamide from lipoic acid and ethylenediamine under an N,N'-carbonyl diimidazole catalyst; and polymerizing thiocinamide, polyethylene glycol diglycidyl ether and lysine through a nucleophilic addition mechanism to prepare a poly(lysine-co-polyethylene glycol diglycidyl ether-co-thiocinamide) terpolymer. The micelle is endowed with excellent anti-protein nonspecific adsorption and enhanced cell uptake property through a self-assembly and protonation/deprotonation action; and a disulfide bond in lipoyl may form a linear polydisulfide structure under the action of 1,4-dithiothreitol, so that a micelle core is crosslinked, and a crosslinked structure is destroyed in the cell under a redox condition, and controlled release of a drug can be achieved. The Nanomicelle of the present invention is expected to be a carrier of drugs for treating cancers.

Preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles

Provided are a reducible degradable hyperbranched-polymer nanomicelle and a method for preparation thereof and an application thereof. Cystamine and polyethylene glycol diglycidyl ether are polymerized by means of a nucleophilic addition mechanism; in one step, a hyperbranched polymer alternatingly arising from cystamine and polyethylene glycol structural units is synthesized and obtained; then, a hyperbranched nanomicelle is formed by means of self-assembly during the process of dialysis. The hyperbranched-polymer chain segments contain both tertiary aminos and disulfide bond structural units and have pH- and reduction responsiveness, and the hyperbranched three-dimensional cavity structure imparts a drug-carrying ability to the nanomicelle.

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Jiangsu, China

Liping Zhang