Zhejiang University

Hangzhou Zeo-innov Life Technology Co., Ltd

Liping Xiao

Jie Fan

Hao Chen

Lisha Yu

Shihui Zou

Xiaoqiang Shang

Wuzhong Yi

Renhong Li

Linfang Lu

Hangping Yao

Dan Li

Yifeng Shi

Provided is a hemostatic composition comprising trypsin and zeolite, wherein pore channels of the zeolite are micropores, the zeolite contains divalent metal cations, and the mass ratio of the trypsin to the zeolite is 1:200-4:10. In the present invention, the trypsin specifically binds to the zeolite, allowing the trypsin to maintain a certain conformation on the surface of the zeolite and to obtain a higher procoagulant activity, thereby obtaining a hemostatic composition with an excellent blood coagulation effect. The hemostatic composition of the present invention has the advantages of a simple preparation method, low cost and convenient use, and can be widely used in hemostasis during trauma and operations, especially in emergent hemostasis in hemophilia patients.

Hemostatic composition and preparation method therefor

A hemostatic compound is provided. The hemostatic compound comprises molecular sieves and a fiber. The molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface. A first surface of the molecular sieve contacted with the fiber is defined as an inner surface, and a second surface of the molecular sieve uncontacted with the fiber is defined as an outer surface. The molecular sieve forms a growth-matched coupling with the fiber on the inner surface, and the growth-matched coupling refers to that a plurality of molecular sieve microparticles grow to match the fiber surface to form a tightly-coupled coupling interface that matches the fiber surface.

Hemostatic compound and preparation method thereof

This disclosure provides a facial green method for metal cyanides preparation, including the following steps: 1) supported metal nanoparticles and Fenton's reagent are mixed with nitrile and then stirred to obtain suspension, wherein metal nanoparticles are selected from a nano metal, nano metal oxide and nano metal salt; 2) centrifuging the suspension to obtain a product and drying the product after stirring to obtain the metal cyanides. As prepared metal cyanides have broad application prospects in the fields of sensor, battery, medicine, electroplating and catalysis. This Fenton-improved cyanation (FIC) method may effectively exclude the toxicity from free cyanide anions and get rid of UV-light, being more energy-saving and more feasible for large-scale industrial production of MCs.

Fenton reagent improved cyanation and usage thereof

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Hangzhou, China

Liping Xiao