Centre Hospitalier Universitaire De Besançon

Centre National De La Recherche Scientifique

Université De Franche Comte

Etablissement Francais Du Sang

Universite De Franche Cornte

Centre Hospitalier Universitaire

Centre Hospitalier Régional Universitaire De Besançon

Archeon

Lionel Pazart

Bruno François Marcel Wacogne

Wilfrid Hervé Boireau

Christian Gérard Daniel Pieralli

Pascal Charles Serge Morel

Sophie Robin

Philippe Humbert

Delphine Binda

Gwenael Rolin

Helene Tauzin

Celine Viennet-Steiner

Fatimata Seydou Sall

Abdo Khoury

Jean-François Vinchant

Céline Viennet-Steiner

Hélène Tauzin

Gwenaël Rolin

Gilles Capellier

Florin Dan Nita

Alban De Luca

Pierre-Edouard Saillard

Youssef Lboutoune

The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatibility of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner. To this end, the system includes a fluidic circuit of a perfusion having a perfusion catheter, a perfusion tubing and a container for the determined perfusion product to be perfused to a patient. The system is also configured to take a body liquid sample from a patient and to analyze and compare the body liquid sample to the determined perfusion product so as to control the flow of the perfusion product.

Secure perfusion system

The invention relates to a device () for taking a sample of a body fluid, such as blood, to be incorporated into a fluid circuit of a perfusion () of a patient who has a perfusion catheter (), said device having a tubular structure () for connecting to the fluid circuit of the perfusion, provided with a zone for intubation, during use, of a sampling channel () comprising a distal end (); and a means () for holding, during use, in the tubular structure, the part of the sampling channel () comprising a distal end () in such a way that the distal end () is oriented towards the perfusion catheter (), in the direction of flow (F) of the perfusion product (), from a perfusion product reservoir () towards the perfusion catheter ().

Device for taking a sample of a body fluid and method for implementing same

The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.

Unshrunken tissue equivalent and methods for producing such an unshrunken tissue equivalent

Growing community of inventors

Besançon, France

Lionel Pazart