Yangtze River Pharmaceutical Group Co., Ltd.

Lingwu Chen

Yongfeng Wang

Xianfeng Lu

Haibo Zhang

Lianyong Shi

Hongpeng Luo

Huixing Liang

The present application discloses an A-type polymorphic substance of yonkenafil hydrochloride and a preparation method, a composition and use thereof. The powder diffraction pattern of the A-type polymorphic substance of yonkenafil hydrochloride comprises diffraction peaks at three or more 2&#x3b8; values selected from: 8.4&#xb1;0.2&#xb0;, 11.3&#xb1;0.2&#xb0;, 13.9&#xb1;0.2&#xb0;, 14.2&#xb1;0.2&#xb0;, 14.7&#xb1;0.2&#xb0;, 16.8&#xb1;0.2&#xb0;, 17.1&#xb1;0.2&#xb0;, 19.7&#xb1;0.2&#xb0;, 21.0&#xb1;0.2&#xb0;, 21.7&#xb1;0.2&#xb0;, 22.4&#xb1;0.2&#xb0;, 23.3&#xb1;0.2&#xb0;, 23.8&#xb1;0.2&#xb0;, 26.8&#xb1;0.2&#xb0;, 27.5&#xb1;0.2&#xb0;, 28.0&#xb1;0.2&#xb0;.

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Jiangsu, China

Lingwu Chen