University of Shanghai for Science and Technology

Chongqing Institute Forfood and Drug Control

Linggao Zeng

Yan Peng

Yiming Zhu

Songlin Zhuang

Chenjun Shi

Xu Wu

Qingrou Yang

A method for qualitative identification and quantitative determination of caffeine in a drug. In the method, terahertz absorption coefficient spectra of drugs with different concentrations of caffeine are measured, from which the frequency points, amplitudes and peak areas of characteristic peaks of the drugs with different concentrations of caffeine are obtained as characteristic quantities. Concentration gradients are established between the concentrations and the characteristic quantities, respectively. The characteristic quantities are imported to the SVR model to establish a training set and a test set. Finally, the qualitative identification and quantitative analysis of caffeine in unknown drugs are achieved.

Method for qualitative identification and quantitative determination of caffeine in drug

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Chongqing, China

Linggao Zeng