Morningside Venture Investments Limited

Chrono Therapeutics Inc.

Ling-Kang Tong

Gary Stacey

Charles Frazer Kilby

Alexander David Norman

Jennifer Darmour

Alan Joel Levy

Congyi Huang

Timothy Charles Frearson

Zita S Netzel

David Evans Roth

Patrick H Ruane

Kevin W Gelston

Jenny E Hapgood

Ronald A Overbeck

Jackie Joe Hancock

Daniela Buchman

Nicholas Terzulli

A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system.

Drug delivery methods and systems

A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

Growing community of inventors

Hayward, CA, United States of America

Ling-Kang Tong