Kimberly-Clark Worldwide, Inc.

Kimberly-Clark Corporation

Linda Susan Huard

David John Tyrrell

David Roland Otts

Brenda Marie Nelson

Bernard Joseph Minerath

Frank Jerrel Akin

Dennis Stein Everhart

Gary Lee Shanklin

Chantel Spring Buhrow

Robert Cosmo DiLuccio

Jian Qin

Tong Sun

Palani Raj Ramaswami Wallajapet

Jacek K Dutkiewicz

Robert Cosmo Di Luccio

Kurt J Bevernitz

Sarah Elizabeth Heathcock

Kevin Gary Korth

Bernard Joseph Iii Minerath

The present invention relates to a method of sequestering skin irritants with a skin irritant sequestering composition comprising a substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. The present invention further also provides a method of sequestering skin irritants comprising administering to the stratum corneum of an individual's skin a skin irritant sequestering composition comprising a substrate, a skin irritant sequestering amount of a combination of hydrophilic and hydrophobic skin irritant sequestering agents. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Method for sequestration of skin irritants with substrate compositions

Facial tissue is provided comprising a tissue substrate, a hydrophilic nasal secretion skin irritant sequestering agent and a hydrophobic nasal secretion skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Facial tissue composition for sequestration of nasal secretion skin irritants

The present invention provides a method of sequestering nasal secretion skin irritants comprising administering to the stratum corneum of an individual's skin a facial tissue comprising a tissue substrate, a nasal secretion skin irritant sequestering amount of a combination of hydrophilic and hydrophobic nasal secretion skin irritant sequestering agents. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Method for sequestration of nasal secretion skin irritants with facial tissue

The present invention relates to a skin irritant sequestering composition comprising a tissue substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment, the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Substrate composition for sequestration of skin irritants

Methods of using absorbent personal care articles, such a diapers and adult incontinent briefs, comprising an absorbent article and having disposed thereon a skin irritant sequestering effective amount of an unmodified particulate skin irritant sequestering agent, and a lipophilic skin health benefit agent are provided. An unmodified particulate skin irritant sequestering agent can be a clay, such as bentonite or laponite unmodified by organic amphiphilic compounds. A lipophilic skin health benefit agent can be stearic acid, isoparrafin, petrolatum, and a combination thereof. The skin irritant can be bound to the sequestering agent either on an individual's skin or on the absorbent article.

Method for sequestration of skin irritants with absorbent article composition

The present invention relates to a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a sacrificial substrate on skin by an aqueous emulsion mediated dissolution of protein from a sheet material with subsequent transfer and deposition onto the skin. Coatings of sacrificial substrate on skin resist removal, thereby providing a protective barrier against chemically- and biochemically-induced skin damage. The treatment composition also provides a vehicle for administering an effective dose of an active agent to the skin surface.

Delivery of a sacrificial substrate to inhibit protease permeation into skin

Absorbent personal care articles, such a diapers and adult incontinent briefs, are provided comprising an absorbent article and having disposed thereon a skin irritant sequestering effective amount of an unmodified particulate skin irritant sequestering agent, and a lipophilic skin health benefit agent. An unmodified particulate skin irritant sequestering agent can be a clay, such as bentonite or laponite unmodified by organic amphiphilic compounds. A lipophilic skin health benefit agent can be stearic acid, isoparrafin, petrolatum, and a combination thereof. The skin irritant can be bound to the sequestering agent either on an individual's skin or on the absorbent article.

Absorbent article composition for sequestering skin irritants

Certain antimicrobial agents, particularly chitosan- or chitin-based polymers, exhibit increased antimicrobial activity when coated onto the surface of a hydrophobic material such as polypropylene. When applied to the surface of a polypropylene nonwoven fabric, for example, the resulting material can be used for diaper liners to reduce odors and promote skin wellness.

Antimicrobial structures

The present invention relates to a method for detecting the presence of P. aeruginosa in a fluid sample. The method uses PCR to amplify the expression of a segment of the exotoxin A gene sequence. The method includes treating strands of nucleotide fragments with a first oligonucleotide primer and a second oligonucleotide primer. The primers are sufficiently complementary to the fragment to hybridize a region having from about 400 to 1200 base pairs. Desirably, the first oligonucleotide primer includes the sequence 5'-ACA ACG CCC TCA GCA TCA CCA-3' and the second oligonucleotide primer includes the sequence 5'-CGG GTC GAG CAG GCA CAA C-3'.

Growing community of inventors

Appleton, WI, United States of America

Linda Susan Huard