Abon Biopharm (hangzhou) Co., Ltd.

Other

Ustar Biotechnologies (hangzhou) Ltd.

Abon Biopharm Co., Ltd.

Lin Hu

Haipeng Hu

Qimin You

Yinfei Wu

Fan Yang

Junli He

Qinhao Yu

Jiayong Gu

Yanqiong Zhou

Huanxin Rao

Sisi Chen

Daisang Wang

Rongyu Jin

Sha Wang

Zhujun Yu

Junwei Yu

Chen Qi

Qinghao Yu

An nucleic acid integrated detection reagent tube is provided, it includes a main tube and one or more branch tubes, wherein a lysing zone, a cleaning zone and a plurality of separation plugs comprising at least a least a separation plug and a second separation plug which are sequentially disposed, the first separation plug is used for separating the lysing zone and the cleaning zone, a reaction zone is provided in the branch tubes and the second separation plug is positioned at a connection between the branch tubes and the main tube or inside the branch tubes; hydrophobic layers in a liquid or a solid phase disposed at each of the plurality of separation plugs; and a magnetic bead channel for magnetically carrying the nucleic acid to sequentially pass through each hydrophobic layer penetrating to the branch tubes defined in an inner wall of the detection reagent tube.

Nucleic acid integrated detection reagent tube

A nucleic acid integrated detection method and detection reagent tube are provided, separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.

Nucleic acid integrated detection method and detection reagent tube

A detection device for detecting analytes in liquid specimen is provided. The detection device comprises: a specimen chamber for collecting or storing a liquid specimen; a detecting chamber for containing a detecting element; and a through hole for transferring the liquid specimen between the specimen chamber and the detecting chamber. The through hole can be opened or self-sealed. The sealing or opening of the through hole controls whether or not the liquid specimen in the specimen chamber enters the detecting chamber via the through hole. Furthermore, a detection method is provided.

Detection device for detecting analytes in liquid specimen

This invention is related to a device for collection and test of fluid specimens, comprising a first cavity and a second cavity; wherein, the first cavity is located inside the second cavity; furthermore, the first and second cavities are interconnected; the said first cavity is available for mutual rotation with the second cavity to facilitate fluid to flow between them; the first cavity is provided with a first position and a second position inside the second cavity. The device of this invention can ensure adequate and uniform mixing of fluid inside the second cavity to facilitate further tests.

Test device for fluid specimens

This invention provides an assay device for testing an analyte in samples, comprising a chamber with an opening for collecting samples, a test element, and a sound indication structure. The indication structure creates sound by vibrating after the structure deforms and would move back to the original position. The assay device is easy to operate for non-professionals.

Assay device for testing an analyte in samples

The invention relates to a method for rapid detection of a target nucleic acid amplification product while preventing cross-contamination between target nucleic acid amplification products and avoiding false positives, comprising the steps of: a) leaving the reaction tube unopened after the amplification reaction is finished, so as to prevent the target nucleic acid amplification product from leaking out and resulting in contamination; b) placing the unopened reaction tube inside an enclosed unit, making the target nucleic acid amplification product be transferred to a test strip from the reaction tube in a physically enclosed environment; c) performing detection in a visual read-out manner, and determining the result; d) discarding the enclosed unit in a safety place as a whole without opening it after the detection. The invention also relates to a totally enclosed unit for detecting a target nucleic acid amplification product, and still relates to applications of the totally enclosed rapid detection unit in detection of infectious pathogens, food industry, agriculture, livestock husbandry, customs quarantine control, and determination of DNA.

Enclosed unit for rapid detection of a target nucleic acid amplification product

Growing community of inventors

Hangzhou, China

Lin Hu