Tongji University

Shanghai Tongji Hospital

Liming Cheng

Jun Wei Zhang

Yan Yu

Rui Zhu

Zhourui Wu

Zhili Zeng

Jianjie Wang

Yongwei Jia

Lie Qian

Rongrong Zhu

Shilong Wang

Application methods of a nano layered double include: applying the nano layered double hydroxide in promoting chondrogenic differentiation of human umbilical cord-derived mesenchymal stem cells, and applying the nano layered double hydroxide in preparing drugs for promoting cartilage regeneration, promoting intervertebral disc repair, or treating intervertebral disc degeneration. Compared to human umbilical cord-derived mesenchymal stem cells without an addition of the nano layered double hydroxide, the human umbilical cord-derived mesenchymal stem cells with the addition of the nano layered double hydroxide have a better and faster ability to differentiate into chondrocytes and broad application prospects.

Application of nano layered double hydroxide in cartilage regeneration and preparation thereof

Disclosed is a nano-layered dual hydroxide-biological factor combined system for promoting nerve regeneration to repair a spinal cord injury. The preparation method therefor comprises: 1) synthesizing a nano-layered dual hydroxide CL1; and 2) co-incubating 10 mg CL1 and 200-2000 ng of biological factors NT3, VEGF or bFGF in a low-speed shaker at 4&#xb0; C. for 2 hours using an ion exchange method, centrifuging same and then obtaining the precipitate. Experiments on transection and resorption spinal cord injury models show that this combined system has a significant recovery effect on the behavior of model mice, can reconstruct the neural circuit of a damaged area over time and achieves an ideal repair effect with regard to a spinal cord injury.

Nano-layered dual hydroxide-biological factor combined system for promoting nerve regeneration to repair spinal cord injury

Techniques are generally described related to a method and system for treating an injury with a bone screw. One example bone screw may be configured to fracture at a pre-selected frangible location so that the point of failure is not in an inaccessible location, e.g., deeply embedded below the surface of a treated bone. The bone screw may further include a material disposed over the frangible location that is designed to temporarily strengthen the screw and selected to be absorbed by the body over a period of time after installation of the screw in the bone. One example bone screw may include an unthreaded portion that is configured to facilitate removal of an embedded screw fragment from a bone in the event that the screw fails in vivo.

Separable pedicle screw

A rod system includes two rods each with a head and a shaft, two elastic members each fitted around one shaft against one head, and a case defining a first inner portion, a second inner portion, and a third inner portion in communication with the first and the second inner portions. A first rod with a first elastic member is seated in the first inner portion so the first elastic member abuts the bottom of first inner portion and the first head protrudes into the third inner portion. A second rod and a second elastic member is seated in the second portion so the second elastic member abuts the bottom of the second inner portion and the second head protrudes into the third inner portion and abuts the first head.

Rod system for gradual dynamic spinal fixation

Growing community of inventors

Shanghai, China

Liming Cheng