Focus Diagnostics, Inc.

Quest Diagnostics Investments, Inc.

Focus Technologies, Inc.

Qiagen Mansfield, Inc.

Bakotic Pathology Associates, LLC

Quest Diagnostics Infectious Disease, Inc.

Lilly I Kong

Jules Chen

Fan Chen

Ming-Chou Lee

Michelle M Tabb

Michael Aye

Mehrdad Jannatipour

Xin Su

Wayne Hogrefe

Jan Groen

Ning Lu

Harry Prince

Sergei Arakelov

Sergey V Voronov

Lori Ilene Bennett

Kiran Madanahally Divakar

Larry McCarthy

Celine Ngo, Legal Representative

Ken Devor

Idowu Akinsanmi

Laurence R McCarthy

Liquan Yang

Marianna Agassandian

Vesselin Tenkov Diankov

Rama Murthy Sakamuri

Erik Gustafson

Ming Chou Lee

Provided herein is a real-time PCR-based method of detecting, in a sample, an agent causing onychodystrophy, wherein the agent causing onychodystrophy belongs to a secondary clade member including one or more primary clade members. Also provided are compositions and kits that finds use in implementing the present method.

Methods of screening for causative agents of onychodystrophy

Disclosed herein are methods and compositions for detectingandby detecting the presence of the IS481 and IS1001 genomic insertion sequences, respectively.

Bordetella detection assay

The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of a BK virus in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved region of BK viral genomes. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.

Methods and compositions for detecting BK virus

detection assay

The present invention generally relates to a molecular test of Influenza A, Influenza B, Respiratory Syncytial Virus A, and Respiratory Syncytial Virus B in order to identify patients with a viral infection. Accordingly methods and compositions are disclosed to determine the presence or absence of a viral pathogen in a sample containing one or more target nucleic acids from the M gene of Influenza A, Influenza B, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B.

Multiplex detection assay for influenza and RSV viruses

Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.

Methods of nucleic acid quantification and detection using anomalous migration

The invention provides methods for sensitive and specific detection of anti-HSV-2 antibodies by depletion of cross-reactive (non-specific) antibodies in a biological sample that can lead to a false positive result. The invention also features compositions, including nucleic acids, polypeptides, and kits, for use in the methods of the invention.

Methods and compositions for detecting herpes simplex virus type 2

The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human rhinovirus (HRV) in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved 5' untranslated region of the HRV genome. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.

Methods and compositions for detecting rhinoviruses

Disclosed are methods of identifying a methicillin-resistant(MRSA) or methicillin-sensitive(MSSA) in a sample. The present invention provides a diagnostic method comprising modification of sequences ofby converting non-methylated cytosine residues ultimately into thymidine residues in the target nucleic acid. The invention further provides for the detection of modified sequences derived from the spa gene, the mecA gene, and the integrated SCCmec cassette of

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Lilly I Kong