The United States of America, As Represented by the Secretary, Department of Health and Human Services

Ericsson Gmbh

Liliana Aidorevich

Christine J Morrison

Errol Reiss

Jong Soo Choi

Nucleic acids for detectingspecies and other filamentous fungi are provided. Unique internal transcribed space 2 coding regions permit the development of nucleic acid probes specific for five different species of, three species of, four species of, two species of, five species of, one species of, as well as probes for, and. Methods are disclosed for the species-specific detection and diagnosis of infection byorin a subject. Furthermore, genus-specific probes are also provided forand, in addition to an all-fungus nucleic acid probe.

Nucleic acids for detecting fusarium species

Nucleic acids for detecting Aspergillus species and other filamentous fungi are provided. Unique internal transcribed space 2 coding regions permit the development of nucleic acid probes specific for five different species of Aspergillus, three species of Fusarium, four species of Mucor, two species of Penecillium, five species of Rhizopus, one species of Rhizomucor, as well as probes for , and . Methods are disclosed for the species-specific detection and diagnosis of infection by Aspergillus, Fusarium, Mucor, Penecillium, Rhizomucor, , Cunninghaemella, Pseudallescheria or Sporthrix in a subject. Furthermore, genus-specific probes are also provided for Aspergillus, Fusarium and Mucor, in addition to an all-fungus nucleic acid probe.

Nucleic acids for detecting Aspergillus species and other filamentous fungi

The present invention provides apparatus and methods in which variable delay is provided for channel tracking. In particular, a demodulator having both a hard output (or symbol estimate) and a soft output (or indication of the quality of the symbol estimate) is coupled to a channel tracker. The channel tracker provides a channel estimate used by the demodulator, in part, to correct for fading. The channel tracker updates the channel estimate based on the symbol estimates from the demodulator and the received signal. However, when the soft output indicates a low confidence in the symbol estimate, the symbol estimate is not used to update the channel estimate. This is accomplished by providing a variable delay to the channel estimate calculation performed by the channel tracker depending on the number of consecutive suspect symbol estimates. For example, a single suspect estimate generates a delay of one causing the most recent estimate to not be used, two consecutive suspect estimate generates a delay of two causing the two most recent estimates to not be used and so on. Accordingly, the channel tracker of the present invention utilizes only the most reliable data available locally to generate a channel estimate for use by the demodulator.

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Maracay, Venezuela

Liliana Aidorevich