Danisco US Inc.

The Procter Gamble Company

Genimmune N.v.

Epimmune Inc.

International N&h Denmark Aps

Dansico US Inc.

Lilia Maria Babe

Frits Goedegebuur

Sina Pricelius

David Aaron Estell

Harm Jan Mulder

Rie Mejldal

Richard Ray Bott

Marc Kolkman

Thijs Kaper

Jian Yao

Eva Maria Perez-Prat Vinuesa

Viktor Alekseyev

Miles Christopher Scotcher

Philip Frank Souter

Michelle Jackson

Katherine Augustyn

Roopa Santosh Ghirnikar

Joshua Roy Basler

Lydia Dankmeyer

Michael Stoner

Anja Hemmingsen Kellett-Smith

Adam Garske

David Marquez

Hatice Billur Engin

Scott Douglas Power

Brian E Jones

Alessandro D Sette

James T Kellis, Jr

Karsten Matthias Kragh

Brian Frederick Schmidt

Zheyong Yu

Zhen Qian

Melodie Estabrook

Robert W Chesnut

Mark Joseph Newman

Yiyou Chen

Gudrun Vogtentanz

Carly Pickering

Brian D Livingston

Sander Van Stigt Thans

Marc Anton Bernhard Kolkman

Lawrence M Deyoung

Carol Marie Fioresi

Igor Nikolaev

Neelam S Amin

David John Tarbit

Anja Hemmingsen Kellett-smith

Brian Sogaard Laursen

Manley T F Huang

Priyanka Chandrasekaran

Sander Van Stigt-Thans

Harm Mulder

Viktor Yuryevich Alekseyev

Jahnavi Chandra Prasad

Xiaogang Gu

Euan John Magennis

Rei Otsuka

Robin Anton Sorg

Victoria Huang

Svend Haaning

Jens Frisbaek Sorensen

Trine Christensen

Anja Hemmingsen Kellett Smith

Nils Henning Redestig

Eva Maria Perez-Prat De Vinuesa

Geetha Veeramuthu

Hye-Sook Kim

H Billur Engin

Shukun Yu

Jeffrey Veach Miller

Lyida Dankmeyer

David A Estell

Munroop Atwal

Anja Hemmingsen

Daniel Esteban Torres Pazmino

Richard R Bott

The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.

Serine proteases

Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

Subtilisin variants

Engineered robust high Tm-phytase clade polypeptides and fragments thereof are described herein. Also described are methods of making such engineered robust high Tm-phytase clade and fragments thereof and use thereof in enhancing animal performance.

Engineered robust high Tm-phytase clade polypeptides and fragments thereof

The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

AprL-clade protease variants and uses thereof

Protease variants and uses thereof

Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning. One embodiment is directed to one or more subtilisin variant, including one or moresp. subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.

Disclosed herein is one or more subtilisin variant. nucleic acid encoding same. and compositions and methods related to the production and use thereof. including one or more-clade subtilisin variant that has improved soil removal compared to one or more reference subtilisin.

-clade serine proteases

A phosphate-free automatic dishwashing cleaning composition comprising i) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 and comprising at least one amino acid substitution (using the SEQ ID NO: 1 numbering) selected from the group consisting of X54T; X126A, D, G, V, E, K, I; X127E, S, T, A, P, G, C; and X128E, C, T, D, P, G, L, Y, N; and ii) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.

Phosphate-free automatic dishwashing detergent compositions having a protease and a complexing agent

Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease has at least 80%, preferably at least 85%, more preferably at least 90% and especially at least 96% identity with the amino acid sequence of SEQ ID NO:1 or with the amino acid sequence of SEQ ID NO:2 and wherein the protease comprises amino acid substitutions selected from the group consisting of:

Automatic dishwashing detergent composition comprising a protease

AprL-clade subtilisin protease variants and uses thereof

An automatic dishwashing cleaning composition having a new protease.

Automatic dishwashing detergent composition

Growing community of inventors

Emerald Hills, CA, United States of America

Lilia Maria Babe