Other

Chinese Academy of Sciences

East China University of Science and Technology

Yunnan University

Lili Zhu

Honglin Li

Zhenjiang Zhao

Hualiang Jiang

Yufang Xu

Yi Tong

Ke Xu

Wenlin Song

Weilie Xiao

Lina Quan

Qiao Li

Yanyan Diao

Provided are applications of a thiazole derivative in treating virus infection and in the preparation of drugs for treating virus infection. Specifically, provided are applications of a compound represented by formula (I) and a pharmaceutical composition comprising the compound represented by formula (I) in treating virus infection and in the preparation of drugs for treating virus infection: 

Applications of novel thiazole derivative in treating virus infection

Provided are use of a saponin compound of formula (I) or (II), or a pharmaceutically acceptable salt, prodrug or solvate thereof, in the manufacture of a medicament targeting PD-1. The medicament targeting PD-1 is one which treats a disease by inhibiting PD-1 from binding to a ligand thereof. The disease may be a tumor, an infection caused by a bacterium, a virus or a fungus, or an inflammatory disease. 

Saponin compound targeting PD-1 and application thereof

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Shanghai, China

Lili Zhu