Chinese Academy of Sciences

Chinese Academy of Medical Sciences

Lili Zhang

Xueli Zhang

Dong Wang

Luqi Huang

Juan Guo

Zhubo Dai

Yi Liu

Ping Gong

Lei Zhang

Dongpo Li

Zhijie Wu

Yuanliang Shi

Shuang Zhang

Cong Ma

Wenlong Duan

Disclosed are a 4-iodopyrazole coordination compound and a preparation method and use thereof. The preparation method includes the following steps: placing CuCl·2HO and 4-iodopyrazole in a container at a certain molar ratio; adding absolute ethanol and dichloromethane to the container at a certain volume ratio to completely dissolve the CuCl·2HO and the 4-iodopyrazole; sealing and puncturing the container, and leaving the container to stand at room temperature for 2-4 days to obtain green bulk crystals; and washing, filtering and drying the green bulk crystals to obtain the 4-iodopyrazole coordination compound. The copper chloride-linked 4-iodopyrazole coordination compound prepared in the present application is a dual-function inhibitor, has a high inhibition rate, low dosage, good stability, difficulty in leaching with water, low toxicity, and low environmental impact, and thus can be used in fertilizers.

4-iodopyrazole coordination compound and preparation method and use thereof

Provided is a recombinant yeast expressing germacrene A synthetase or a fusion protein thereof, wherein the fusion protein is germacrene A synthetase and farnesyl pyrophosphate synthase. The recombinant yeast improves the yield of germacrene A, and is suitable for the industrialized production of β-elemene and/or germacrene A.

Recombinant yeast and use thereof

An application of farnesene in preparing a plant-derived urease inhibitor is provided. The compound can effectively inhibit activities ofurease and soil urease, and has an effect that is equivalent to that of commercial urease inhibitor acetohydroxamic acid. The urease inhibitor in the present disclosure, derived from plants, has 'pollution-free' characteristics of natural products, high biological safety, simple and stable chemical structure and remarkable urease inhibition effect, can solve the problems of conventional chemically-synthesized urease inhibitor such as high toxicity, easy degradation and poor stability, also provides a new concept for creating a biological ecological technology for efficiently inhibiting the rapid hydrolysis of urea in farmland and increasing the utilization rate of urea nitrogen fertilizer, and has good application value and development prospect.

Application of farnesene in preparing plant-derived urease inhibitor

Provided is a recombinant yeast expressing germacrene A synthetase or a fusion protein thereof, wherein the fusion protein is germacrene A synthetase and farnesyl pyrophosphate synthase. The recombinant yeast improves the yield of germacrene A, and is suitable for the industrialized production of &#x3b2;-elemene and/or germacrene A.

Growing community of inventors

Tianjin, China

Lili Zhang