Advanced Micro Devices Corporation

Chinese Academy of Sciences

Shanghai Lead Discovery Pharmaceuticals Limited Company

Lili Chen

Jing Lan Chen

Wei Han

Hong Tao Liu

Hualiang Jiang

Fei Ye

Kaixian Chen

Jingkang Shen

Tao Sun

Jianping Zuo

Jianhua Shen

Bing Xiong

Xiaomin Luo

Xu Shen

Yiming Yang

Haibin Luo

Donglu Bai

Yifu Yang

Xianhan Zhuang

Xuchang He

KaiFei Zhao

JunDong Yang

Chunshan Gui

A computer-implemented method for data communication bus address sharing can include selecting, by at least one processor, one of two or more peripheral devices sharing an address of a data communication bus. The method can additionally include modulating, by the at least one processor, a duty cycle of a clock signal transmitted over the data communication bus to the two or more peripheral devices, wherein the modulating causes a low period of the clock signal to satisfy a threshold condition for indicating selection of the selected one of the two or more peripheral devices. The method can also include performing, by the at least one processor using the address, data communication over the data communication bus with the selected one of the two or more peripheral devices. Various other methods, systems, and computer-readable media are also disclosed.

Systems and methods for data communication bus address sharing

A method for operating a system including a voltage regulating power supply includes sensing a local voltage on a first node of the system and a remote voltage on a second node of the system. The first node and the second node are in a conductive path coupled to a load of the system. The first node is closer to a power stage of the voltage regulating power supply than the second node. The second node is closer to the load than the first node. The method includes detecting a load release event based on the local voltage, the remote voltage, and at least one predetermined threshold value.

Method to reduce overshoot in a voltage regulating power supply

The present invention discloses 3D-structure of SARS-CoV Viral 3CL Protease obtained through molecular simulation. The 3D-structure is used as a drug target for screening the existing medical database CMC (Comprehensive Medicinal Chemistry, MDL Information System, Inc.), and a group of compounds which have the activity of inhibiting SARS-CoV virus 3CL Protease are found. Cinanserin was tested at molecular and viral levels, and it was found to be able to inhibit the SARS-CoV viral 3CL protease and SARS-CoV viruses. Cinanserin analogs were synthesized and tested at molecular and viral levels, they were found to be able to inhibit the SARS-CoV virus 3CL Protease and SARS-CoV viruses, and may be used for treating and/or preventing SARS-CoV virus infection.

3D-structure model of SARS coronavirus 3CL protease and anti-SARS drugs

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Lili Chen