Sichuan Kelun Pharmaceutical Research Institute Co. Ltd.

Likai Yang

Jingyi Wang

Lichun Wang

Dong Zhao

Fengying Shan

Zhengxing Su

Kexing Wang

Jing Zhou

Yujun Wang

Disclosed herein is an albumin pharmaceutical composition, comprising albumin and at least one amino acid having a relative molecular mass of 145-175. Clinically, the albumin pharmaceutical composition can effectively reduce undesirable responses, such as rash, urticaria, anaphylaxis and possible immune responses in the human body caused by albumin polymers and dimers, thereby further ensuring the safety in clinical medication.

Albumin pharmaceutical composition and preparation method therefor

The present invention relates to a docetaxel albumin nanoparticle pharmaceutical composition, a preparation method therefor, and a use thereof for manufacturing drugs for treating cancer. The pharmaceutical composition comprises docetaxel, albumin and amino acid(s), wherein the weight ratio between albumin and docetaxel is no more than 50, preferably is 20:1 to 1:1, and the weight ratio between amino acid(s) and docetaxel is not less than 0.5, preferably is 1:1 to 20:1.

Docetaxel albumin nanoparticle pharmaceutical composition, preparation method therefor and use thereof

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Sichuan, China

Likai Yang