Tasly Pharmaceutical Group Co., Ltd.

Lijun Fan

Xijun Yan

Yongfeng Zheng

Naifeng Wu

Shunnan Zhang

Wensheng Zhang

Kaijing Yan

Zhengliang Ye

Lihong Zhou

Hai'ou Dong

Xiaobing Sun

Xiaohui Ma

Hongbo Zhang

He Sun

Jing Wang

Xiaolin Bai

Yi He

Shuiping Zhou

Yan Liu

Xiaofeng Liu

Yan Sun

Changsheng Rong

Chenming Li

Xiaofeng LiU

Xinxin Li

Jianhui Yang

Lina Dong

Yiqian Zhang

Jiawen Shi

Xiaoqing Li

Cong Chen

Jingjing Zhang

Shiqing Wang

Yan Fu

Xingyun Shao

Song Gao

Bo Xu

Changyu Ma

Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.

Pharmaceutical composition and application thereof

A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.

Traditional Chinese medicine composition, and preparation and application thereof

The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.

Formulation of a micro drop pill and the preparation method thereof

An air-cooling micro drop pill capsule production line comprises a drop pill system, an air-cooling circulation system and a control system. The drop pill system comprises a molten material tank and a dripper. A vibration apparatus is arranged between the molten material tank and the dripper, and drives the dripper to vibrate up and down. A vibration shear force cuts liquor flowing out from the dripper into drops, and drop pills are formed after the drops fall into the air-cooling circulation system and are cooled. An online monitoring apparatus is arranged on the dripper, and comprises a pulse signal emission mechanism with an emission frequency which is the same as a vibration frequency of the vibration apparatus. The control system controls and regulates a dropping parameter according to a monitoring result of the online monitoring apparatus. The present invention combines vibration dropping, online monitoring and controlling, air cooling, and fluidized drying and coating together, which satisfies the requirement of high-speed dropping, micro pill preparation and improving a drug-loading capacity. Thus, the drug-loading capacity of drop pills can be multiply improved, the usage of auxiliary materials and the dosage can be greatly reduced, organic solvent residual can be completely avoided, and requirements of different processes including slow-release coating, film coating and sugar coating can be satisfied.

Air-cooling micro drop pill capsule production line

Traditional chinese medicine composition, and preparation and application thereof

A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root,, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell,tuber, and, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.

Pharmaceutical composition for treating headache, and preparation method thereof

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Tianjin, China

Lijun Fan