Alpharma Pharmaceuticals LLC

Lijuan Tang

Alfred Liang

Garth Boehm

Frank Matthews

Frank L Johnson

Joseph Stauffer

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.

Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist

Pharmaceutical compositions for the deterrence and/or prevention of abuse

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated.

Pharmaceutical composition

Pharmaceutical compositions

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Flemington, NJ, United States of America

Lijuan Tang