Edwards Lifesciences Corporation

Lien Huong Thi Hoang

Son V Nguyen

Diana Nguyen-Thien-Nhon

Dinesh L Sirimanne

Kevin D Rupp

Hien Tran Ngo

Kim D Nguyen

Michael C Murad

Russell Thomas Joseph

Michael R Bialas

Vivian Tran

Quang Ngoc Vu

Gil Senesh

Brendan Michael Dalbow

Jeanette Jasmine Corona

Gonzalo German Angelico

Ashley Akemi Ishigo

Taylor Michael Winters

Kristen Hicks

Vicky Hong Do

Carla Susana Cerqueira

Victoria Mariko Low

Andrea Fernandez

Karl J Britzman

Haley Nicole Whitehead

Shannon Nicole Hoye

Jeannette Jasmine Corona

A prosthetic heart valve includes an annular frame that is radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The frame has a plurality of circumferentially extending rows of angled struts, each row of angled struts comprising angled struts arranged in a zig-zag pattern. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame. The sealing member has an undulating outflow edge portion forming a plurality of triangular projections that are connected to and shaped to correspond to the zig-zag pattern of one of the rows of angled struts. The outer sealing member is sized to fit snugly against the outer surface of the frame when the frame is in the expanded configuration.

Sealing member for prosthetic heart valve

A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.

Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one embodiment, a prosthetic heart valve can include a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and attached to struts of the frame forming the selected cell, and commissure tabs of two adjacent leaflets coupled to the attachment member, and a radiopaque marker arranged on the attachment member of the commissure. The marker is configured to indicate a location of the commissure of the prosthetic heart valve.

Commissure marker for a prosthetic heart valve

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San Juan Capistrano, CA, United States of America

Lien Huong Thi Hoang