Massachusetts Institute of Technology

National University of Singapore

Bruker Spatial Biology, Inc.

Lidan Wu

Joseph M Beechem

Jongyoon Han

Dwayne L Dunaway

Joel Voldman

Rustem Khafizov

Mark Gregory

Dae Kim

Guofeng Guan

Chwee Teck Lim

Hao-Wei Su

Jaemyeong Jung

Ali Asgar Bhagat

Chong Jin Ong

Majid Ebrahimi Warkiani

Javier Lopez Prieto

Chao Yu Peter Chen

Kah Ping Andy Tay

Evan Perillo

Jonathan Cheng

Isabel Lee

Shanshan He

Tushar Rane

A system for intra-operative blood salvage autotransfusion is provided. The system comprises at least one inlet configured to receive whole blood of a patient; at least one curvilinear microchannel in fluid flow connection with the at least one inlet, the at least one curvilinear microchannel being adapted to isolate circulating tumor cells in the whole blood, based on cell size, along at least one portion of a cross-section of the at least one curvilinear microchannel; and at least two outlets in fluid flow connection with the at least one curvilinear microchannel, at least one outlet of the at least two outlets being configured to flow the circulating tumor cells isolated from the whole blood, and at least one other outlet of the at least two outlets being configured to flow at least a portion of a remainder of the whole blood, cleansed of the isolated circulating tumor cells, for return to the patient.

System and method for inertial focusing microfiltration for intra-operative blood salvage autotransfusion

A system includes a microfluidic device configured to isolate one or more particles from a mixture, a flow rate matching device configured to match flow rate of the microfluidic device with flow rate of an electrical measurement device configured to measure an electrical property of the isolated particles, and an electrical measurement device configured to measure an electrical property of the isolated particles.

Integrated electrical profiling system for measuring leukocytes activation from whole blood

A micro-fluidic device includes at least one inlet and a curvilinear microchannel having a trapezoidal cross section defined by a radially inner side, a radially outer side, a bottom side, and a top side, the cross section having a) the radially inner side and the radially outer side unequal in height, or b) the radially inner side equal in height to the radially outer side, and wherein the top side has at least two continuous straight sections, each unequal in width to the bottom side.

Micro-fluidic device and uses thereof

Growing community of inventors

Cambridge, MA, United States of America

Lidan Wu