Boehringer Mannheim Italia

Boehringer Mannhein Italia, S.p.a.

Licia Gallico

Silvano Spinelli

Roberto Di Domenico

Giorgio Long

Carmelo A Gandolfi

Sergio Tognella

Bruno Lumachi

Antonella Rozzi

Ernesto Menta

Giampiero De Cillis

Simonetta D'Alo'

Gianpiero De Cillis

Simonetta D'Alo

1,4-disubstituted piperazines useful in the therapy of the asthma and of

##STR1## Compounds of formula (I), having antiasthmatic and antiinflammatory actions on the respiratory tract, processes for the preparation thereof and pharmaceutical compositions containing them.

[3H,7H]thiazole[3,4-a]pyridines having antiasthmatic and

Heterocyclic amines useful in the therapy of asthma and imflammation of

[3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory

Compounds of formula I ##STR1## wherein Ar is an optionally substituted phenyl ring; B is a single bond, a group --(CH.sub.2 OCH.sub.2).sub.n being n=or 2, a a 2,4-disubstituted-1,3-dioxolane ring or a 2,4-disubstituted-1,3-thioxolane ring, R is a single bond, an optionally substituted methylene or ethylene group and T is 2, 3- or 4-pyridyl, an optionally salified or esterified carboxy group or a carboxyamide group. Said compounds are useful in treatment of respiratory diseases.

Ethers and thioethers having therapeutical activity, their preparation

.beta.-carbonyl-carboxyamides of 1,3-thiazolidines

Compounds of formula I ##STR1## wherein Ar is an optionally substituted phenyl ring; B is a single bond, a group --(CH.sub.2 OCH.sub.2).sub.n being n=1 or 2, a 2,4-disubstituted-1,3-dioxolane ring or a 2,4-disubstituted-1,3-thioxolane ring, R is a single bond, an optionally substituted methylene or ethylene group and T is 2-, 3- or 4-pyridyl, an optionally salified or esterified carboxy group or a carboxyamide group. Said compounds are useful in treatment of respiratory diseases.

Growing community of inventors

Milan, Italy

Licia Gallico