Zhejiang Huahai Pharmaceutical Co., Ltd.

Libin Hu

Zhiyun Wang

Hao Chen

Min Li

Jinsheng Lin

Wenquan Zhu

Dan Li

Tianpei Huang

Xiaoyan Xu

Xiangjie Shi

Xinshi Wang

Feifei Lan

Jiening Liu

Disclosed is N-formyl vortioxetine, and also disclosed is a method for preparing the N-formyl vortioxetine and a stable solid preparation of vortioxetine.

N-formyl vortioxetine and preparation method thereof and solid preparation of vortioxetine

Disclosed is a preparation method for an azacitidine for injection, wherein each injection vial of azacitidine for injection contains 100 mg of azacitidine and 100 mg of mannitol. The preparation method comprises the steps of measuring 80% of the total volume of water for injection at a temperature of 2-6&#xb0; C.; adding mannitol, and stirring to completely dissolved at a temperature of 2-6&#xb0; C.; adding azacitidine, stirring to completely dissolved at a temperature of 2-6&#xb0; C. to obtain an azacitidine solution for injection; filling each injection vial with 23 ml azacitidine solution for injection after filtration; freeze-drying at a preset temperature; and stoppering, capping and packaging after nitrogen filling. The preparation method has the advantages of a simple process, low energy consumption, high production efficiency and stable product quality.

Preparation method of azacitidine for injection

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Zhejiang, China

Libin Hu