Wisconsin Alumni Research Foundation

The Ohio State University

Lianwang Guo

Shaoqin Gong

Guojun Chen

K Craig Kent

Bowen Wang

Go Urabe

The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Growing community of inventors

Columbus, OH, United States of America

Lianwang Guo