Temasek Life Sciences Laboratory Limited

Joil (s) Pte Ltd.

Lianghui Ji

Yanbin Liu

Lin Cai

Chong Mei John Koh

Si Te Ngoh

Longhua Sun

Sihui Amy Yap

Chong Mei Koh

Lin Fu

Nam-Hai Chua

Hsin I Cheng

Ni Peng

Madhaiyan Munusamy

Cai Lin

A culture for the fermentative production oflactone comprising anspecies in a culture medium, wherein thespecies expresses no functional Aureobasidin A synthase gene mRNA when cultured, the culture medium including KHPO, NaHPO, (NH)SO, MgSO·7HO and CaCl·2HO; at least two trace elements selected from the group consisting of Fe, Cu, Znand MoO; urea; and a carbon source selected from the group consisting of glucose, mannose, xylose and mixtures thereof, wherein the culture medium has a pH from 5.5 to 6.5.

Methods for fermentative production of massoia lactone

The present invention relates to the field of fermentation biotechnology, more particularly to methods for the fermentative production of massoia lactone byspecies.

The present invention relates to the field of molecular biology and more particularly to promoters useful for metabolic engineering in yeast or fungi for the production of biobased chemicals with broad applications. Intron-containing promoters with strong activity during oil-accumulation stages are particularly useful for genetic engineering in yeast and fungi, particularlyorgenera. Such promoter are capable of driving strong expression of RNA or proteins in species of theorgenera.

Intron-containing promoters and uses thereof

The present invention relates to the field of fungal production fatty alcohols. More specifically, the present invention relates to genetically modified host cells, nucleic acid constructs and culture medium for the production of fatty alcohols in

Production of fatty alcohols in Rhodosporidium

The present invention relates to the field of the production of transgenic plants through-mediated transformation of cells of somatic embryogenic calli or embryogenic suspension cultures and regeneration of the transformed cells into fruit-setting plants. In particular, the present invention relates to the production of transgenic plants in the Euphorbiaceae family. The present invention further relates to media compositions, selection methods and engineeredstrains that improve-mediated transformation efficiency.

strains for plant transformation

The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of carotenoids in fungal hosts selected fromandgenera.

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The present invention relates to the application of isolated promoters and synthetic constructs for efficient production of genetically modified cells in a species selected from the Pucciniomycotina and Ustilaginomycotina subphyla, in particular, species selected from theor

Polynucleotide sequences from rhodosporidium and rhodotorula and use thereof

The present invention relates to the field of fungal biotechnology, more particularly to a strong inducible gene expression system in fungal species, such as a species of thegenus or thegenus.

The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected fromandgenera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.

The present invention relates to methods of reducing chemical fertilizer usage and greenhouse gas nitrous oxide emission and to methods of improving plant growth rate and seed productivity in agriculture through the application of a novel artificially manufactured formula containing a nitrogen-fixing bacterium that efficiently colonizes non-legume plants in aerial parts and the root system. The bacteria inocula and methods are particularly suitable for plants in the generaand

Nitrogen-fixing bacterial inoculant for improvement of crop productivity and reduction of nitrous oxide emission

The present invention relates to the field of somatic embryo production, particularly to methods for the regeneration ofthrough somatic embryogenesis. More specifically, the present invention relates to a method and media compositions for regeneration of plants of. The method is well suited fortransformation and for producing clonal planting stock useful for large scaleplantation.

A group of genes including GhCIR1 from cotton (), and AtCIR1 and AtCIR2 frompromote shoot regeneration in plants even in the absence of cytokinin. In the presence of cytokinin, the genes significantly improve transformation efficiency. The genes can be used as an enhancer as well as a selectable marker of transformation in plants. The proteins encoded by the novel genes have a homeodomain (HD) at the N-terminus and a highly divergent domain at the C-terminus. The proteins share a common structural motif.

Plant homeodomain protein-encoding genes and their uses

The present invention provides methods for high efficiency plant transformation via-mediated T-DNA conjugation to suspension-cultured cells or calli. The methods described herein employ membranes or filters as porous solid support for the co-culture of T-DNA donor and recipient.

Growing community of inventors

Singapore, Singapore

Lianghui Ji