Tsinghua University

Capitalbio Corporation

Capitalbio Ehealth Science & Technology (beijing) Co., Ltd.

Chongqing Ehealth Jiuyetang Biological Technology Co., Ltd.

Capitalbiochip Corporation

Liangbin Pan

Jing Cheng

Wanli Xing

Guangxin Xiang

Jing Zhu

Cheng Chen

Yuxiang Zhou

Zhongyao Yu

Zhe Li Yu

Youchun Xu

Lihua Huang

Haoying Shao

A liquid storage and release chip provided according to the present application includes a structural layer and an elastic cover sheet. An end surface of one side of the structural layer is provided with a liquid storage cell and a liquid quantitation cell, the liquid storage cell and the liquid quantitation cell are separated by a common partition wall, and the partition wall is provided with a valve opening passing through end surfaces of two sides of the structural layer. The elastic cover sheet is attached to the structural layer and covers the liquid storage cell, the liquid quantitation cell and the valve opening in a sealed manner, and the valve opening allows a spool to be inserted in the valve opening in a sealed manner to push up a portion, covering the valve opening, of the elastic cover sheet.

Liquid storage and release assembly and liquid storage and release chip

A microelectrode sensing device includes a substrate and an array of microelectrode sensors. Each sensor includes a first conductive layer that at least partially conducts electricity. The first conductive layer is formed above the substrate and patterned to include a recording electrode that measures electrical activities of target cells. Each sensor also includes a second conductive layer that at least partially conducts electricity. The second conductive layer is elevated above the first layer and patterned to include multiple positioning electrodes arranged to define a sensing region above the recording electrode. The positioning electrodes are designed to generate an electric field pattern in the sensing region to move and confine the target cells to a sub-region of the sensing region that at least partially overlaps the recording electrode.

Automatic positioning and sensing microelectrode arrays

The present invention provides an apparatus for stimulating an animal cell and recording its physiological signal and methods of making and using thereof. The purpose of the present invention is to provide an apparatus for stimulating an animal cell and recording its physiological signal that is efficient, convenient, and accurate. The apparatus for stimulating an animal cell and recording its physiological signal of the present invention comprises a poor conductive substrate, wherein on at least one surface of the substrate is provided at least one unit conductive polymer layer and at least one good conductive microelectrode.

Apparatus for stimulating an animal cell and recording its physiological signal and production and use methods thereof

Growing community of inventors

Beijing, China

Liangbin Pan