Yangtze River Pharmaceutical Group Co., Ltd.

Shanghai Haiyan Pharmaceutical Technology Co., Ltd.

Liang Zhang

Jiong Lan

Fusheng Zhou

Qi Yang He

Yunzhou Jin

Xiangyu He

Ping Bu

Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derivatives of formula (I) are described in the specification. 

Azabicyclo derivatives, process for preparation thereof and medical use thereof

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Shanghai, China

Liang Zhang