Shenyang Pharmaceutical University

Jinzhou Jiutai Pharmaceutical Co., Ltd., China

Liaoning Zhuanglong Unmanned Aerial Vehicle Technology Co., Ltd.

Li Zhang

Maosheng Cheng

Li Pan

Lie Ji

Jianmin Shen

Guilan Song

Zhiging Li

Shiquan Guo

Mingfei Chen

Xiangqun Guo

Xin Xu

Youdong Wang

Kuiwen Zhang

Jingjing Wang

The invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein Ris H, chlorine, or bromine; Ris electron attractive groups selected from the group consisting of CF, CN, fluorine, CHSO, CFSO, and NO; Ris linear or branched alkyl having 1 to 10 carbon atoms, linear or branched alkoxyalkyl having 2 to 10 carbon atoms, aliphatic alcohol having 1 to 10 carbon atoms, or cycloalkyl having 3 to 6 carbon atoms. The invention also relates to methods for preparing the said compounds and the composition comprising the same. The compounds of the present invention have the effect of &#x3b2;-receptor agonist and can be used for the treatment of asthma and bronchitis 

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Shenyang, China

Li Zhang