Chinese Academy of Agricultural Sciences

Wuhan Norrida Biotechnological Co., Ltd

Li Yu

Peiwu Li

Zhaowei Zhang

Xiao Chen

Guohui Zhou

Xiupin Wang

Ling Cheng

Decheng Yang

Haiwei Wang

Wenqin Wu

The present disclosure belongs to the technical field of biosensors and particularly provides a construction method for a photocathode indirect competition sensor and an evaluation method. The construction method includes: using Z-type BiO/CuBiOas a sensing platform; calculating a photoinduced electron Z-type transfer path and an energy band structure of BiOand CuBiOusing a density functional theory (DFT); and constructing a BiO/CuBiO-based biosensor. A photoelectrochemical (PEC) photocathode biosensor based on a BiO/CuBiOheterojunction prepared through the solution has good repeatability, reproducibility, stability, and specificity for detecting a target. The PEC biosensor constructed in the solution of the present disclosure has a broad application prospect in the fields of healthcare, environment, and food.

Construction method for photocathode indirect competition sensor and evaluation method

A temperature-sensitive attenuated FMDV strain, construction method and applications thereof. The construction method of the temperature-sensitive attenuated FMDV strain is as follows. Mutating a cytosine on K region loop of IRES domain 4 of an FMDV genome to a guanine or an adenine to obtain the temperature-sensitive attenuated FMDV strain, or replacing a K region of IRES domain 4 of an FMDV genome with a K region of IRES domain 4 of a bovine rhinovirus genome to obtain the temperature-sensitive attenuated FMDV strain.

Temperature-sensitive attenuated FMDV strains, construction method and application thereof

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Harbin, China

Li Yu