Tsinghua University

Food Industry Research and Development Institute

Gp Medical, Inc.

Li-Wen Hsu

Hosheng Tu

Hsing-Wen Sung

I-Ching Chen

Ha Giang Thi Nguyen

Fang Yi Su

Chien-Hsun Huang

Sung-Yuan Hsieh

Chien-Chi Chen

Jong-Shian Liou

Er-Yuan Chung

Disclosed herein is an isolated strain ofHGM001, which is deposited at Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH under an accession number DSM 34119. A method for producing butyric acid using the isolated strain ofHGM001, a fermented culture produced by the method, and a method for alleviating an inflammatory disorder using the fermented culture are also disclosed.

HGM001 isolate and use thereof

The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.

Pharmaceutical composition of nanoparticles

Growing community of inventors

Hsinchu, Taiwan

Li-Wen Hsu