Biotyx Medical (shenzhen) Co. Ltd.

Lifetech Scientific (shenzhen) Co., Ltd

Huawei Technologies Co., Limited

Shenzhen Yinwang Intelligent Technologies Co., Ltd.

Lifetech Scientific Co., Ltd.

Li Qin

Wenjiao Lin

Deyuan Zhang

Haiping Qi

Hongtao Sun

Ziqiang Liu

Gui Zhang

Liping Chen

Jun Hu

Huafeng Wen

Wen Hu

Wenchao Fu

Wenhai Wang

Zhenjian Lin

An implantable device including a matrix and a zinc-containing layer at least partially covering the substrate. The zinc-containing layer includes a zinc compound. The ratio of the mass of the zinc element in the zinc-containing layer to the surface area of the implantable device is 0.1-200 μg/mm2. The average porosity of the zinc-containing layer is 30% or less. By matching the ratio of the mass of zinc in the zinc-containing layer to the surface area of the implantable device with the average porosity of the zinc-containing layer, the release rate of zinc is controlled within a reasonable range so that the rate of formation of the zinc-containing substance is controlled such that the concentration of the zinc-containing substance accumulated in the tissue is higher than the concentration which inhibits the proliferation of smooth muscle cells, and is always lower than the toxic concentration which causes cell death.

Implantable device

Disclosed is a vehicle control method, including: obtaining a first velocity planned for an intelligent vehicle to travel in a first area; and obtaining a second velocity planned for the vehicle to travel in the first area, where the second velocity is obtained based on a collision potential energy, the first velocity and the second velocity each include a direction and a magnitude, and the first velocity, the second velocity, and a risk of a collision between the vehicle and a surrounding obstacle are used to determine an optimal velocity of the vehicle, so that the vehicle can effectively avoid the obstacle, thereby improving traveling safety of the vehicle. Also disclosed are a vehicle control apparatus, a vehicle controller, and a vehicle.

Vehicle control method

An implantable device including a metal substrate; that contains particles having a size of 1 μm or more; if the wall thickness of the metal substrate is greater than or equal to 0.04 mm and less than or equal to 0.12 mm, the largest particle size is less than or equal to 15 μm and the average content of the particles is less than or equal to 40 ppm; if the wall thickness of the metal substrate is greater than 0.12 mm and less than or equal to 0.2 mm, the largest particle size is less than or equal to 20 μm and the average content of the particles is less than or equal to 100 ppm; The size of the particles and the average content of the particles are reasonably controlled according to the wall thickness of the metal substrate, improving the plastic deformation capability of the implantable device.

A stent and a preparation method therefor. The stent includes a stent substrate. The stent substrate is provided with at least one radiopaque structure thereon. Each radiopaque structure includes at least one radiopaque unit. A radiopaque material is inlaid in each radiopaque unit, and a ratio of the volume of the radiopaque material to the volume of the radiopaque unit ranges from 1.1 to 1.4. By the stent and the preparation method therefor, the interference fit between the radiopaque material and the radiopaque unit can be better implemented, so that the radiopaque material and the radiopaque unit have strong bonding force therebetween, and the problem of embolism caused by the drop of a radiopaque material is avoided.

Stent and preparation method therefor

An absorbable implantable medical device made of iron-based alloy, including a base made of iron-based alloy and a complex, wherein the complex includes a complexing agent. In a physiological solution, the base made of iron-based alloy can react with the complexing agent to generate a water-soluble iron complex having solubility in the physiological solution of no less than 10 mg/L. A corrosion product generated after the absorbable implantable medical device made of iron-based alloy is implanted in a human body can be quickly metabolized/absorbed by the body.

Absorbable iron-based alloy implanted medical device

A radiopaque structure and an implanted medical instrument having the radiopaque structure. The radiopaque structure includes at least one radiopaque unit, and each radiopaque unit includes at least one radiopaque object. In at least one incidence direction of a light source, all the radiopaque objects in the radiopaque structure are divided into n regions according to the thickness in the incidence direction, and a projection area Sm of m regions of the n regions and an effective thickness dm of the m regions meet Sm&#x2212;0.0136(dm)a&#x2265;0, wherein &#x2212;0.95&#x2264;a&#x2264;&#x2212;0.85 and 1&#x2264;m&#x2264;n. The radiopaque structure has good or excellent visibility.

Radiopaque structure and implanted medical device having radiopaque structure

An absorbable iron-based alloy implantable medical device includes an iron-based alloy matrix, a degradable polymer coating disposed on the surface of the iron-based alloy matrix, and a corrosion inhibition layer disposed on the surface of the iron-based alloy matrix. The corrosion inhibition layer can delay early-stage corrosion of the iron-based alloy matrix, ensure mechanical performance of a medical device in the early stage of the implantation, prevent degradation of a polymer in the early stage of the implantation of the medical device, and reduce the usage of the degradable polymer, thereby reducing risks of inflammatory reactions.

Absorbable iron-based alloy implantable medical device

Provided are an iron-based absorbable and implantable medical device and manufacturing method thereof. The iron-based absorbable and implantable medical device () comprises a substrate (), a degradable polymer layer (), and an anionic surfactant layer () located between the substrate () and the degradable polymer layer (). The anionic surfactant, by using the hydrophobicity thereof, can form a hydrophobic barrier layer in a solution to isolate a surface of the iron-based substrate () from a body fluid environment, thereby avoiding direct contact with an acidic environment resulting from degradation of the degradable polymer layer () at the initial and early stages of implantation, thus preventing severe local corrosion of the iron-based substrate ().

Iron-based absorbable and implantable medical device and manufacturing method thereof

Absorbable iron-based alloy implanted medical device and manufacturing method thereof. The iron-based alloy implanted medical device comprises an iron-based alloy substrate (), a degradable polymer layer () disposed on a surface of the iron-based alloy substrate (), and a tannic acid chemical conversion film () disposed on a surface of the iron-based alloy substrate (). After the medical device is implanted into a body, the tannic acid chemical conversion film () is configured to protect the iron-based alloy substrate () coated thereby from being in contact with a body fluid, thereby ensuring that the device meets a clinical mechanical property requirement in the early stage of implantation. Furthermore, the iron-based alloy implanted medical device has a decreased size, and produces a decreased amount of a corrosive product after being implanted, facilitating faster absorption or elimination of the corrosive product.

Absorbable iron-based alloy medical instrument implant and manufacturing method

The invention discloses an absorbable iron-based alloy stent, comprising an iron-based alloy substrate and a degradable polyester in contact with the surface of the substrate, in which the degradable polyester has a weight average molecular weight of between 20,000 and 1,000,000 and a polydispersity index of between 1.2 and 30. With the degradable polyester, the iron-based alloy is capable of corroding rapidly and controllably within a predetermined period. Following implantation into the human body, the degradable stent serves as a mechanical support at early stage, then gradually degrading and being metabolized and absorbed by the human body. During the process of degradation, minimal or no solid product is produced. Ultimately, the configuration of the lumen with an implanted stent as well as the systolic and diastolic functions thereof return to their natural states.

Bioresorbable iron-based alloy stent

A method and an apparatus for topology discovery are disclosed. Link state information of each port of each device on a ring network is confirmed through neighbor negotiation between a first device and a neighbor device, and by broadcasting a link state information base of each device to other devices on the ring network, each device on the ring network can obtain the newest and synchronous link state information of each port on the ring network, so that each network device on the ring network implements topology discovery of the ring network where the network device is located.

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Shenzhen, China

Li Qin