Onquality Pharmaceuticals China Ltd.

Leying Chen

Shiyi Zhang

Chao Liu

Jie Luo

Zhaoyu Wu

Xin Zhao

Rui Xing

Songxuan Sun

Linan Yang

Zhehui Gong

The present application relates to use of a nitric oxide releasing agent in the preparation of a medicament for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor. The present application further provides a method for preventing or treating diseases or disorders associated with administration of a VEGFR inhibitor and/or VEGF inhibitor in a subject. The method comprise administering, to a subject in need, a prophylactically or therapeutically effective amount of the nitric oxide releasing agent.

Method of preventing or treating side effect of tumor therapy

The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.

Method for preventing or treating diseases associated with the inhibition of EGFR

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Shanghai, China

Leying Chen