Sophrosyne Pharmaceuticals Limited

Lewis Feldberg

Vincent Wing-Fai Tai

Akram Sabouni

Thomas R Bailey

Tom Leyssens

Provided herein are novel crystalline forms of a compound that acts as an ALDH2 effector, processes for preparing the crystalline forms of the compound with or without coformer, and uses thereof.

Crystalline forms of ALDH2 modulators

The disclosure is directed to, in part, compounds, or pharmaceutically acceptable salts or solvates thereof, for modulating the activity of aldehyde dehydrogenase such as ALDH2 and/or methods for treating and/or preventing an alcohol related disorder such as alcohol use disorder, alcohol induced disorder, alcohol abuse, alcohol dependence, alcohol intoxication, alcohol withdrawal, and the like and/or methods for reducing the amount of alcohol consumed, reducing alcoholic cravings, or increasing the percentage of no heavy drinking days for a subject with alcohol use disorder.

Growing community of inventors

Montclair, NJ, United States of America

Lewis Feldberg