Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Levava Roiz

Oded Shoseyov

Betty Schwartz

Patricia Smirnoff

Raphael Goren

Ben-Ami Bravdo

Uzi Ozeri

A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.

Methods of and compositions for inhibiting the proliferation of mammalian cells

The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof.

Recombinant human T2 RNase and uses thereof

A method for the biological control of pollen in plants, including the thinning of fruits, reducing seeds in citrus plants and reducing the incidence of shotberries in grapes, by applying an effective amount of activated or inactivated RNase or mixtures of these to the flowers of the plants.

Growing community of inventors

Kiryat-Ono, Israel

Levava Roiz