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Institut Organicheskoi Khimii Akademii Nauk Ukrainskoi Ssr

Institut Organischskogo Sinteza Akademii Nauk Ssr

Lev Moiseevich Yagupolsky

Sergei Vasilievich Sokolov

Viktor Mikhailovich Belous

Alexei Ivanovich Ponomarev

Ljubov Antonovna Alexeeva

Gunar Y Dubur

Rasma O Vitolin

Miron Onufrievich Lozinsky

Vladlen Vasilievich Malovik

Valeria V Kastron

Jury Pavlovich Dolnakov

Vsevolod Volfovich Berenblit

Alexandr Leibovich Klebansky

Boris Efimovich Gruz

Julia Alexeevna Larionova

Agris A Kimenis

Natalya V Kondratenko

Vladimir I Popov

Alexandr A Kolomeitsev

Rufina Mikhailovna Ryazanova

Anatoly Kirillovich Ankudinov

Tatyana Ivanovna Rymareva

Valery Y Semeny

Jury A Fialkov

Svetlana V Shelyazhenko

Konstantin N Bildinov

Alexandr V Kirsanov

Ninel G Feschenko

Alexandr Vasilievich Karlin

Vasily Danilovich Lobkov

Petr V Serebrov

Alevtina A Goncharenko

Guntis V Zarinsh

Marita Y Selga

Elena L Khanina

Vladimir Leibovich Liverant

Mikhail I Lyapunov

Mira Semenovna Kopylova

Lidia Ivanovna Petrik

Iosif Yakubovich Kalantarov

Faina Borisovna Timashpolskaya

Idima Evgenievna Meitus

Andrei Yakovlevich Ilichenko

Vladimir N Zavatsky

Elena Alexeevna Fedorovskaya

The present invention relates to organic chemistry. The novel compound 2-oxo-4-(2'-difluoromethylthiophenyl)-5-methoxycarbonyl-6-methyl-1,2,3,4-t etrahydropyrimidine has the formula: ##STR1## Said compound displays coronary-dilating activity and can be utilized in medicine.

2-oxo-4-(2'-difl

The present invention relates to derivatives of 1,4-dihydropyridine and, more specifically, to 2,6-dimethyl-3,5-dicarbomethoxy-4-(o-difluoromethylthiophenyl)-1,4-dihydro pyridine having the formula ##STR1## The proposed compound features pronounced hypotensive activity of prolonged duration and is capable of producing a coronarodilating effect while having low toxicity and being useful for treating diseases of the cardiovascular system.

2,6-Dimethyl-3,5-dicarbomethoxy-4-(ortho

The present invention relates to derivatives of 1,4-dihydropyridine and, more specifically, to 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihydro pyridine of the formula: ##STR1## This compound features a clearly pronounced hypotensive activity while being low-toxic, wherefore it can be used in medicine for treating hypertensive disease.

2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(ortho-difluoromethoxyphenyl)-1,4-di

Novel compounds, viz., tris(perfluoroalkyl)phosphine oxides have the following general formula ##STR1## where R.sub.F is a perfluoroalkyl of normal and iso-structure, having from 2 to 8 carbon atoms. The method of preparing said compounds consists in that trialkylphosphine oxide having the general formula R.sub.3 PO, where R = C.sub.8 -C.sub.8, is fluorinated electrochemically in a medium of anhydrous hydrogen fluoride; whenever trialkylphosphine oxides having the general formula R.sub.3 PO, where R = C.sub.5 - C.sub.8, are used as the starting material, they are first brominated in a medium of anhydrous hydrogen fluoride, with subsequent isolation of the end product. The proposed novel compounds can be used as solvents for salts of rare earth elements and as complexing agents in the separation of valuable metals.

Method of tris(perfluoroalkyl)phosphine oxides

A method and composition for producing a bactericidal active monochlorotriazine dye, by reacting active dichlorotriazine dye with a bactericidal compound containing hydroxyl or amino groups. The reaction is run in an aqueous, organic, or water-organic medium at 20.degree.-40.degree. C. The monochlorotriazine dye thus formed is active and possesses bactericidal properties. On dyeing fibres, it endows them with high bactericidal properties retained after repeated wet treatments.

Bactericidally active monochlorotriazine dyes

The present invention relates to aryl perfluoro-alkyl ethers that are compounds of the general formula: ##STR1## where R.sub.F .dbd. CF.sub.3 or CF.sub.2 OCF.sub.3, X.dbd. Br;

Aryl perfluoro-alkyl ethers and method of producing them

The present invention relates to fluorosiloxane diols of the formula ##STR1## where: R.sub.F = OCF.sub.3, OC.sub.2 F.sub.5, OC.sub.2 F.sub.4 OCF.sub.3, C.sub.2 F.sub.4 OCF.sub.3, C.sub.3 F.sub.7,

Fluorosiloxane diols and method of producing same

The present invention relates to fluorosiloxane rubbers of the formula: ##STR1## wherein: R.sub.F = OCF.sub.3, OC.sub.2 F.sub.5, OC.sub.2 F.sub.4 OCF.sub.3, C.sub.2 F.sub.4 OCF.sub.3, C.sub.3 F.sub.7,

Fluorosiloxane rubbers and process for producing same

The invention relates to [perfluoroalkyl(alkoxy)phenyl]methyldichlorosilanes characterized by the general formula ##STR1## where: R.sub.F = OCF.sub.3 OC.sub.2 F.sub.5, OC.sub.2 F.sub.4 OCF.sub.3, C.sub.2 F.sub.4 OCF.sub.3, C.sub.3 F.sub.7 and also to a method of preparing them. The method according to the invention consists in that fluorobromo[alkyl(alkoxy)]benzenes having the general formula ##STR2## where: R.sub.F = OCF.sub.3 OC.sub.2 F.sub.5, OC.sub.2 F.sub.4 OCF.sub.3, C.sub.2 F.sub.4 OCF.sub.3, C.sub.3 F.sub.7 are treated with magnesium taken in a 5 - 20 per cent excess with respect to the stoichiometric quantity in a solution of absolute diethyl ether or absolute tetrahydrofurane at a temperature of 8.degree. - 60.degree. C. The resulting fluorine-containing magnesiumbromo[alkyl(alkoxy)]benzenes are treated with three-functional silanes -- methyltrichlorosilane -- taken in a 100 - 500 per cent excess with respect to the stoichiometric quantity, or with methylchlorodiethoxysilane, taken in the stoichiometric quantity or in a 50 per cent excess with respect to the stoichiometric quantity, at a temperature of 18.degree. - 60.degree. C. In the case of methylchlorodiethoxysilane, the resultant product is fluorine-containing [alkyl(alkoxy)phenyl]methyldiethoxysilanes which are treated with acetyl chloride taken in a 25 - 50 per cent excess with respect to the stoichiometric quantity, at a temperature of 40.degree. - 70.degree. C, in the presence of ferric chloride as a catalyst. The proposed [perfluoroalkyl(alkoxy)phenyl]methyldichlorosilanes can be used for preparing organofluosilicon lubricants, greases, sealing counds, rubber mixtures having high resistance to heat, frost, petrol and oils, that can be used in various fields of technology. The described method can be used to obtain the proposed end products in yields as high as 96 per cent of theory.

[Perfluoroalkyl(alkoxy)phenyl]methyldichlorosilanes and method of

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Kyiv, Ukraine

Lev Moiseevich Yagupolsky