Permeable Technologies, Inc.

Lester Weintraub

Mohammed I Ali

Harry J Spinelli

Leonard Seidner

Waifong Liew Anton

Henry D Coleman

Paul White

The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicon-containing acrylic star polymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment. Described is a copolymer comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one monomer selected from the group consisting of silicone acrylates, esters of alpha, beta-unsaturated acids and wetting monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The copolymer is readily machined into gas permeable contact lenses exhibiting substantially enhanced characteristics of at least one of the characteristic group of oxygen permeability, hardness and machineability relative to contact lenses formed from the random polymerization of monomers.

Silicone-containing contact lens polymers, oxygen permeable contact

The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicone-containing acrylic star polymers, graft copolymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment. Described is a composition comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one hydrophilic monomer and at least about 5% by weight of a polysiloxanylalkylester of an alpha, beta unsaturated acid and optionally, monomers selected from the group consisting of esters of alpha, beta-unsaturated acids and crosslinking monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The final compositions are hydrated to a final water content of at least about 10% by weight.

Silicone-containing polymers, compositions and improved oxygen permeable

The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicone-containing acrylic star polymers, graft copolymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment. Described is a composition comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one hydrophilic monomer and optionally, monomers selected from the group consisting of silicone acrylates, esters of alpha, beta-unsaturated acids and crosslinking monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The final compositions are hydrated to a final water content of at least about 10% by weight.

Silicone-containing polymers, oxygen permeable hydrophilic contact

The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicone-containing acrylic star polymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment. Described is a copolymer comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one monomer selected from the group consisting of silicone acrylates, esters of alpha, beta-unsaturated acids and wetting monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The copolymer is readily machined into gas permeable contact lenses exhibiting substantially enhanced characteristics of at least one of the characteristic group of oxygen permeability, hardness and machineability relative to contact lenses formed from the random polymerization of monomers.

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Mount Laurel, NJ, United States of America

Lester Weintraub