Harvard College

Leonid Peshkin

Marc W Kirschner

Graeme C McAlister

Steven P Gygi

Wilhelm Haas

Martin Helmut Wuhr

Ramin Rad

Graeme Conrad Mcalister

Graeme Conrad McAlister

Embodiments are directed to a method, a computer readable medium encoded with instructions that, when executed, perform a method, and a system for performing mass spectrometry analysis. Molecules of different samples may be labeled with a chemical tag, allowing a multiplexed analysis of multiple samples. The labeled molecules may be fragmented, each fragmented molecule creating at least two separate ions. The relative abundance of each of the heavier ions, which may comprise the original molecule from the sample, may be measured. A relative abundance of the labeled molecules in each of the samples may be determined from the measured relative abundances of the heavier ions.

Accurate and interference-free multiplexed quantitative proteomics using mass spectrometry

Growing community of inventors

Boston, MA, United States of America

Leonid Peshkin