Advanced Bionics Ag

Advanced Bionics Corporation

Medtronic, Inc.

Advanced Biomes Ag

Advance Bionics, LLC

Academisch Ziekenhuis Leiden

Leonid Michael Litvak

Aniket Saoji

Kanthaiah Koka

Abhijit Kulkarni

Lakshmi Narayan Mishra

Gene Y Fridman

Edward Holman Overstreet

Lee F Hartley

Mark B Downing

Smita S Agrawal

R Tissa Karunasiri

Anthony J Spahr

Tracey L Kruger

William Vanbrooks Harrison

Philip A Segel

Guillermo A Calle

Avram Scheiner

Michael Allen Faltys

Matthew Isaac Haller

James B Hissong

Touby Austin Drew

Sean Patrick Skubitz

Thomas I Miller

Kristin N Hageman

Volkmar Hamacher

Adam J Rivard

David J Miller

Kurt J Koester

Chen Chen

Dean Swan

Charles C Finley

Gulamali Emadi

Gulam Emadi

Adam Strauss

Patrick T Wong

Nobutaka Okuyama

John Norris

Jason Galster

Hannah A Glick

Amy Stein

Erik J Peterson

Manohar Joshi

Kinuko Masaki

Robert T Sandgren

Andrew Jay Cleland

Bing Xu

Patrick Joseph Boyle

Roger Calixto

Eugene Kim

Brian Andrew Smith

Andrew Perry Quick

Michael Stanley Marzalek

Juan G Hincapie

Waldo Nogueira

Myles McLaughlin

Jeffery M Kramer

Todd D Zenisek

David A Krubsack

Mary Elizabeth Bush

William L Johnson

Hansjuerg Emch

Johannes HM Frijns

Adam B Strauss

Aniket S Saoji

Edward H Overstreet

An exemplary diagnostic system is configured to direct an acoustic stimulation generator to an acoustic stimulation generator to apply acoustic stimulation having a plurality of stimulus frequencies to a recipient of a cochlear implant during an insertion procedure in which an electrode lead communicatively coupled to the cochlear implant is inserted into a cochlea of the recipient, direct the cochlear implant to use an electrode disposed on the electrode lead to record a plurality of evoked response signals during the insertion procedure, each evoked response signal included in the plurality of evoked response signals corresponding to a different stimulus frequency included in the plurality of stimulus frequencies, and determine, based on an amplitude and a phase of each of one or more evoked response signals included in the plurality of evoked response signals, an insertion state of the electrode lead within the cochlea of the recipient.

Use of one or more evoked response signals to determine an insertion state of an electrode lead during an electrode lead insertion procedure

An example method of delivering electrical stimulation includes obtaining, by an implantable medical device (IMD) connected to a lead carrying a plurality of electrodes, one or more stimulation parameters; and delivering, by the IMD and based on the one or more stimulation parameters, electrical stimulation therapy via the plurality of electrodes, wherein delivering the electrical stimulation therapy comprises scanning delivery of the electrical stimulation therapy through different pairs of electrodes of the plurality of electrodes.

Neurostimulation using time-interleaved cascade of bipolar electrode combinations

An illustrative system includes a stimulation device configured to apply stimulation to a recipient, a sensing device configured to detect a physiological condition of the recipient, and a processing unit communicatively coupled to the stimulation device and the sensing device. The processing unit determines a stimulation strategy that is customized to the recipient and includes stimulation frames and stimulation gaps. The processing unit then directs the stimulation device to apply the stimulation to the recipient in accordance with the stimulation strategy by applying the stimulation only during time that corresponds to the stimulation frames. The processing unit also directs the sensing device to detect the physiological condition of the recipient in accordance with the stimulation strategy by detecting only during time that corresponds to the stimulation gaps. Based on the detected physiological condition, the processing unit performs an action. Corresponding systems, methods, and apparatuses are also disclosed.

Systems and methods for monitoring and acting on a physiological condition of a stimulation system recipient

An illustrative cochlear implant system includes an electrode lead having an array of electrodes, a cochlear implant coupled with the electrode lead and configured to be implanted within a recipient together with the electrode lead, and a processing unit communicatively coupled to the cochlear implant. The processing unit is configured to direct the cochlear implant to apply stimulation to the recipient by way of the array of electrodes. The processing unit is further configured to detect, by way of one or more electrodes included in the array of electrodes, a cortical potential produced by the recipient. Based on the detected cortical potential, the processing unit is configured to determine a fitting parameter associated with the cochlear implant system. Corresponding systems and methods are also disclosed.

Systems and methods for fitting a hearing system to a recipient based on cortical potentials of the recipient

An illustrative system includes a coil configured to be positioned over a wound on a body and held in place on the body by a magnet implanted within the body; and a controller communicatively coupled to the coil, the controller configured to apply therapeutic electromagnetic pulses by way of the coil to the wound. Other systems and methods for providing therapeutic electromagnetic pulses to a recipient are also disclosed.

Systems and methods for providing electromagnetic therapy to an implantable device recipient

An illustrative scalar translocation detection system directs a loudspeaker to apply acoustic stimulation to a cochlear implant patient while an electrode lead is inserted into a cochlea of the cochlear implant patient. The system detects a first evoked response to the acoustic stimulation while an electrode is positioned at a first location in the cochlea and detects a second evoked response to the acoustic stimulation while the electrode is positioned at a second location in the cochlea. Then, based on at least one of an amplitude change or a phase change between the first and second evoked responses, the system determines that a scalar translocation of the electrode lead from one scala of the cochlea to another scala of the cochlea has occurred. Based on this determination, the system also notifies a user that the scalar translocation has occurred. Corresponding methods and systems are also disclosed.

Scalar translocation detection for an electrode lead of a cochlear implant system

A medical system for obstructive sleep apnea (OSA) treatment includes therapy delivery circuitry configured to output one or more electrical stimulation signals to a tongue of a patient; sensing circuitry configured to sense one or more compound muscle action potential (CMAP) signals, wherein the one or more CMAP signals are generated in response to the delivery of the one or more electrical stimulation signals; and processing circuitry configured to: cause the therapy delivery circuitry to output the one or more electrical stimulation signals to the tongue; receive information indicative of the one or more CMAP signals from the sensing circuitry; determine, based on the one or more CMAP signals, one or more therapeutic stimulation parameters for the OSA treatment; and cause the therapy delivery circuitry to deliver therapeutic electrical stimulation signals according to at least the determined one or more therapeutic stimulation parameters.

Stimulation therapy for treating obstructive sleep apnea (OSA) based on compound muscle action potential (CMAP)

An illustrative system includes a cochlear implant, a lead configured to be inserted into a cochlea of a patient by way of an insertion procedure, a plurality of electrodes disposed on the lead and including an intracochlear electrode and an extracochlear electrode, a probe coupled to the extracochlear electrode, and a processor communicatively coupled with the probe and the cochlear implant. During the insertion procedure, the processor directs the cochlear implant to short the intracochlear and extracochlear electrodes, then detects, by way of the probe and the shorted intracochlear and extracochlear electrodes, evoked responses measured at the intracochlear electrode. The evoked responses include a first evoked response measured at a first insertion depth and a second evoked response measured at a second insertion depth. The processor generates, based on the first and second evoked responses, a notification indicating that cochlear trauma has likely occurred at the second insertion depth.

Systems and methods for intra-surgical monitoring of cochlear trauma during an electrode lead insertion procedure

An illustrative proximity detection system directs a first electrode of an electrode lead to apply a first pulse and directs a second electrode of the electrode lead to apply a second pulse concurrently with the first pulse so as to form a dipole that generates a field. The first and second electrodes are each configured as stimulating electrodes that apply stimulation to the cochlear tissue when the electrode lead is located at a resting position subsequent to a surgical insertion of the electrode lead into a cochlea of a patient. After the pulses are applied, and based on an energy magnitude of the field that is detected to reflect from cochlear tissue located within the field, the proximity detection system determines a proximity of the electrode lead to the cochlear tissue. Corresponding systems and methods are also disclosed.

Systems and methods for detecting electrode lead proximity to cochlear tissue

An exemplary diagnostic system may be configured to direct an acoustic stimulation generator to apply acoustic stimulation to a recipient of a cochlear implant during an insertion procedure in which an electrode lead coupled to the cochlear implant is supposed to be inserted into a cochlea of the recipient, direct the cochlear implant to use an electrode on the electrode lead to record an evoked response signal that occurs within the recipient in response to the acoustic stimulation, detect an anomaly in the evoked response signal, and determine, based on the anomaly, that the electrode lead is being inserted into a vestibular canal instead of into the cochlea.

Intraoperative detection of electrode lead misplacement during a lead insertion procedure

A system for selecting a sensitivity level for adjusting an intensity setting for therapy provided to a patient includes one or more processors and one or more processors coupled to the memory. The one or more processors are configured to receive an indication of an input to adjust an intensity setting related to the therapy provided to the patient and determine a sensitivity level for adjustment of the intensity setting based on an efficacy of the therapy provided to the patient. The one or more processors are further configured to determine an updated intensity level for the intensity setting based on the sensitivity level and the input to adjust the intensity setting and output an instruction to cause a medical device to provide the therapy at the updated intensity level.

Patient-learned control of medical device

An apparatus external to a patient and communicatively coupled to an implant within the patient is disclosed. The apparatus identifies a tentative stimulation parameter adjustment constraint and an absolute stimulation parameter adjustment constraint for a stimulation parameter associated with the implant. The apparatus also determines an impedance of an electrode implanted within the patient and coupled with the implant. Based on the impedance of the electrode, the apparatus automatically adjusts the stimulation parameter within a range between a present value and a first value defined by the tentative stimulation parameter adjustment constraint. Additionally, based on user input manually provided by the patient, the apparatus further adjusts the stimulation parameter within a range between the first value and a second value beyond the first value and defined by the absolute stimulation parameter adjustment constraint. Corresponding apparatuses, systems, and methods are also disclosed.

Apparatuses and methods for managing stimulation parameters for an implant

An exemplary scalar translocation detection system detects a first evoked response occurring in response to acoustic stimulation applied to a cochlear implant patient. The system detects the first evoked response by way of an electrode configuration disposed on an electrode lead while the electrode configuration is positioned at a first location along an insertion path of the electrode lead into a cochlea of the patient. The system further detects, by way of the electrode configuration while it is positioned at a second location along the insertion path, a second evoked response occurring in response to additional acoustic stimulation applied to the patient. The system further determines an amplitude change and/or a phase change between the first and second evoked responses, and then determines whether a scalar translocation of the electrode lead from one scala of the cochlea to another has occurred based on the amplitude change and/or the phase change.

Systems and methods for detecting a scalar translocation of an electrode lead within a cochlea of a cochlear implant patient

A cochlear implant system may include a cochlear implant configured to be implanted within a user and a sound processor configured to detect an amount of sound exposure to the user; gradually adjust a most comfortable level ('M level') from an initial value towards a target value in accordance with an adaption time course and in accordance with the detected amount of sound exposure to the user by increasing the M level when the detected amount of sound exposure is above a first threshold and decreasing the M level when the detected amount of sound exposure is below a second threshold; and direct the cochlear implant to apply stimulation having the gradually adjusted M level to the user.

Systems and methods for gradually adjusting a control parameter associated with a cochlear implant system

An exemplary system includes a coil configured to be positioned over a wound on a body and held in place on the body by a magnet implanted within the body. The system further includes a controller communicatively coupled to the coil and configured to apply therapeutic electromagnetic pulses by way of the coil to the wound. Other systems and methods for providing therapeutic electromagnetic pulses to a recipient are also disclosed.

Growing community of inventors

Los Angeles, CA, United States of America

Leonid Michael Litvak